Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL130_RS02360 Genome accession   NZ_LR134320
Coordinates   454362..455618 (+) Length   418 a.a.
NCBI ID   WP_002283524.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 449362..460618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS02340 - 450337..450615 (-) 279 Protein_409 transposase -
  EL130_RS02345 (NCTC10832_00439) mutL 450840..452795 (+) 1956 WP_002283525.1 DNA mismatch repair endonuclease MutL -
  EL130_RS02350 (NCTC10832_00440) ruvA 452978..453571 (+) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  EL130_RS02355 (NCTC10832_00441) - 453653..454213 (+) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  EL130_RS02360 (NCTC10832_00442) cinA 454362..455618 (+) 1257 WP_002283524.1 competence/damage-inducible protein A Machinery gene
  EL130_RS02365 (NCTC10832_00443) recA 455658..456809 (+) 1152 WP_002283523.1 recombinase RecA Machinery gene
  EL130_RS02370 (NCTC10832_00444) spx 456894..457292 (+) 399 WP_002262391.1 transcriptional regulator Spx -
  EL130_RS02375 (NCTC10832_00445) - 457543..457968 (+) 426 WP_002266116.1 hypothetical protein -
  EL130_RS02380 - 458109..458309 (+) 201 Protein_417 hypothetical protein -
  EL130_RS02385 (NCTC10832_00446) brsM 458300..458746 (-) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  EL130_RS02390 (NCTC10832_00447) brsR 458759..459193 (-) 435 WP_002277469.1 bacteriocin genes transcriptional regulator BrsR Regulator
  EL130_RS02395 (NCTC10832_00448) - 459361..459630 (+) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  EL130_RS02400 (NCTC10832_00449) ruvX 459627..460046 (+) 420 WP_002277470.1 Holliday junction resolvase RuvX -
  EL130_RS02405 (NCTC10832_00450) - 460127..460426 (+) 300 WP_002262384.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45749.48 Da        Isoelectric Point: 5.7659

>NTDB_id=1121406 EL130_RS02360 WP_002283524.1 454362..455618(+) (cinA) [Streptococcus mutans strain NCTC10832]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKT
IITIDNLADYFYGYGEENSLPQVVFDLLKEKDKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQVHGVVSAFTAEKMAERSRQLTQADLAISLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1121406 EL130_RS02360 WP_002283524.1 454362..455618(+) (cinA) [Streptococcus mutans strain NCTC10832]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGACA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGATAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAAGTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTATTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(259-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.282

100

0.993
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.531

100

0.715
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.005

98.804

0.455

Multiple sequence alignment