Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   EL130_RS02390 Genome accession   NZ_LR134320
Coordinates   458759..459193 (-) Length   144 a.a.
NCBI ID   WP_002277469.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 453759..464193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS02360 (NCTC10832_00442) cinA 454362..455618 (+) 1257 WP_002283524.1 competence/damage-inducible protein A Machinery gene
  EL130_RS02365 (NCTC10832_00443) recA 455658..456809 (+) 1152 WP_002283523.1 recombinase RecA Machinery gene
  EL130_RS02370 (NCTC10832_00444) spx 456894..457292 (+) 399 WP_002262391.1 transcriptional regulator Spx -
  EL130_RS02375 (NCTC10832_00445) - 457543..457968 (+) 426 WP_002266116.1 hypothetical protein -
  EL130_RS02380 - 458109..458309 (+) 201 Protein_417 hypothetical protein -
  EL130_RS02385 (NCTC10832_00446) brsM 458300..458746 (-) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  EL130_RS02390 (NCTC10832_00447) brsR 458759..459193 (-) 435 WP_002277469.1 bacteriocin genes transcriptional regulator BrsR Regulator
  EL130_RS02395 (NCTC10832_00448) - 459361..459630 (+) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  EL130_RS02400 (NCTC10832_00449) ruvX 459627..460046 (+) 420 WP_002277470.1 Holliday junction resolvase RuvX -
  EL130_RS02405 (NCTC10832_00450) - 460127..460426 (+) 300 WP_002262384.1 DUF1292 domain-containing protein -
  EL130_RS02415 (NCTC10832_00451) - 460660..462231 (+) 1572 WP_002264553.1 membrane protein -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 17250.32 Da        Isoelectric Point: 10.7353

>NTDB_id=1121409 EL130_RS02390 WP_002277469.1 458759..459193(-) (brsR) [Streptococcus mutans strain NCTC10832]
MKLKIIKDSNFKEPLLQIYTRHIDKQTQRVIDFIQQRPNIVYGYKNKRLEFIPLEKVIRIFTENKQVLIQTPTDIYLAKQ
RLYFFEQELGTPFIRISQGEIINIKYIKQLNLTIRGSIEVTFKNGTVSFVARRSLKRFKEQLNL

Nucleotide


Download         Length: 435 bp        

>NTDB_id=1121409 EL130_RS02390 WP_002277469.1 458759..459193(-) (brsR) [Streptococcus mutans strain NCTC10832]
ATGAAATTAAAAATTATCAAGGATTCAAACTTTAAGGAACCCTTACTCCAAATCTATACACGTCATATTGATAAACAAAC
GCAAAGAGTGATTGATTTTATTCAACAAAGACCTAATATCGTTTATGGTTACAAAAATAAACGCTTAGAGTTTATCCCAC
TAGAAAAAGTGATTCGTATTTTCACGGAAAACAAACAGGTCTTAATTCAAACACCAACCGATATCTATTTAGCTAAACAA
AGACTCTACTTTTTTGAGCAAGAATTAGGAACACCTTTTATTCGTATCTCCCAAGGTGAAATCATCAATATCAAATATAT
TAAACAATTAAATTTAACCATCCGAGGCAGCATTGAAGTGACTTTCAAAAATGGAACAGTCAGTTTCGTGGCTAGGCGAA
GTTTGAAACGCTTCAAAGAACAATTAAATCTTTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(48-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

97.222

100

0.972

Multiple sequence alignment