Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsM   Type   Regulator
Locus tag   EL130_RS02385 Genome accession   NZ_LR134320
Coordinates   458300..458746 (-) Length   148 a.a.
NCBI ID   WP_002262388.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   repress competence development; negative regulate BrsR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 453300..463746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS02355 (NCTC10832_00441) - 453653..454213 (+) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  EL130_RS02360 (NCTC10832_00442) cinA 454362..455618 (+) 1257 WP_002283524.1 competence/damage-inducible protein A Machinery gene
  EL130_RS02365 (NCTC10832_00443) recA 455658..456809 (+) 1152 WP_002283523.1 recombinase RecA Machinery gene
  EL130_RS02370 (NCTC10832_00444) spx 456894..457292 (+) 399 WP_002262391.1 transcriptional regulator Spx -
  EL130_RS02375 (NCTC10832_00445) - 457543..457968 (+) 426 WP_002266116.1 hypothetical protein -
  EL130_RS02380 - 458109..458309 (+) 201 Protein_417 hypothetical protein -
  EL130_RS02385 (NCTC10832_00446) brsM 458300..458746 (-) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  EL130_RS02390 (NCTC10832_00447) brsR 458759..459193 (-) 435 WP_002277469.1 bacteriocin genes transcriptional regulator BrsR Regulator
  EL130_RS02395 (NCTC10832_00448) - 459361..459630 (+) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  EL130_RS02400 (NCTC10832_00449) ruvX 459627..460046 (+) 420 WP_002277470.1 Holliday junction resolvase RuvX -
  EL130_RS02405 (NCTC10832_00450) - 460127..460426 (+) 300 WP_002262384.1 DUF1292 domain-containing protein -
  EL130_RS02415 (NCTC10832_00451) - 460660..462231 (+) 1572 WP_002264553.1 membrane protein -

Sequence

Protein


Download         Length: 148 a.a.        Molecular weight: 17106.61 Da        Isoelectric Point: 10.1992

>NTDB_id=1121408 EL130_RS02385 WP_002262388.1 458300..458746(-) (brsM) [Streptococcus mutans strain NCTC10832]
MKILKQIITYSFIGIGIGSLMNYFIAIFFFPNSNPLGVPSFVQLFSSVSQATAVQLFIFALLGVLQGFASSLFKNEKLSL
LTTSLIHYLFIVLPLLLAGSYLHWFYMTRKYFVFSFLLVSIIYILIYLFCYFENKKNIQKINKKLHQI

Nucleotide


Download         Length: 447 bp        

>NTDB_id=1121408 EL130_RS02385 WP_002262388.1 458300..458746(-) (brsM) [Streptococcus mutans strain NCTC10832]
ATGAAAATACTCAAACAGATTATTACTTACAGTTTTATTGGTATAGGAATCGGTTCTTTAATGAATTATTTCATAGCCAT
CTTCTTTTTCCCAAATAGTAATCCACTTGGTGTCCCAAGTTTTGTTCAACTTTTTTCATCAGTTTCACAGGCAACAGCAG
TCCAACTTTTCATTTTTGCTCTTCTAGGCGTTTTACAAGGATTTGCTAGCAGCCTCTTTAAAAATGAAAAACTCAGTCTA
CTAACCACAAGCTTGATTCACTATTTATTCATTGTCCTACCACTTCTCTTAGCCGGATCTTATTTACACTGGTTTTACAT
GACTCGGAAATATTTCGTTTTTTCTTTCCTTTTGGTTTCTATTATTTATATCCTCATTTACTTATTCTGCTATTTTGAAA
ATAAAAAAAACATTCAAAAAATCAATAAGAAGCTGCATCAAATATAA

Domains

Predicted by InterproScan.

Protein of unknown function (DUF3021) (DUF3021)

(5-145)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsM Streptococcus mutans UA159

100

100

1

Multiple sequence alignment