Detailed information NTG1120233

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: EL087_RS01005
• Genome accession: NZ_LR134288
• Coordinates: 190391..190819 (+)
• Length: 142 a.a.
• NCBI ID: WP_037566697.1
• Uniprot ID: A0A4U9Y4F2
• Organism: Streptococcus milleri strain NCTC11169
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 185391..195819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL087_RS00975 (NCTC11169_00190)	-	185849..186208 (+)	360	WP_003028467.1	MerR family transcriptional regulator	-
EL087_RS00980 (NCTC11169_00191)	glnA	186246..187592 (+)	1347	WP_106079126.1	type I glutamate--ammonia ligase	-
EL087_RS00985 (NCTC11169_00192)	-	187777..188142 (+)	366	WP_126406228.1	DUF1033 family protein	-
EL087_RS00990 (NCTC11169_00193)	comYA	188212..189153 (+)	942	WP_126406231.1	competence type IV pilus ATPase ComGA	Machinery gene
EL087_RS00995 (NCTC11169_00194)	comYB	189095..190117 (+)	1023	WP_182465780.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL087_RS01000 (NCTC11169_00195)	comYC	190114..190431 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
EL087_RS01005 (NCTC11169_00196)	comYD	190391..190819 (+)	429	WP_037566697.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL087_RS01010 (NCTC11169_00197)	comGE/cglE	190791..191084 (+)	294	WP_126406234.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL087_RS01015 (NCTC11169_00198)	comGF/cglF	191068..191505 (+)	438	WP_049513212.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL087_RS01020 (NCTC11169_00199)	comGG	191486..191812 (+)	327	WP_269470973.1	competence type IV pilus minor pilin ComGG	-
EL087_RS01025 (NCTC11169_00200)	comYH	191884..192837 (+)	954	WP_003039058.1	class I SAM-dependent methyltransferase	Machinery gene
EL087_RS01030 (NCTC11169_00201)	-	192884..194083 (+)	1200	WP_126406237.1	acetate kinase	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 16276.72 Da
• Isoelectric Point: 10.4191

>NTDB_id=1120233 EL087_RS01005 WP_037566697.1 190391..190819(+) (comYD) [Streptococcus milleri strain NCTC11169]
MRNIQKKLVPLQIKGFTLLESLLTLFITSFLLLAVSGSVRSSFEQVEEQIFFLEFEHFYRESQKLSSSAQSQLDMNFSRE
RISNGYNRLAVPRSIQAPEDLTLHFDKAGGNSSLGKIVFQTKKQTVTYQLYLGNGKFKKTTR

Nucleotide

• Length: 429 bp

>NTDB_id=1120233 EL087_RS01005 WP_037566697.1 190391..190819(+) (comYD) [Streptococcus milleri strain NCTC11169]
ATGCGAAACATACAAAAGAAGCTCGTTCCGTTGCAGATTAAGGGATTTACGCTTTTGGAAAGTTTGCTGACTTTATTTAT
AACGAGTTTCTTATTGCTTGCTGTGTCGGGCTCTGTTCGTTCTTCTTTTGAACAGGTGGAAGAGCAGATTTTCTTTCTGG
AGTTTGAGCATTTTTATCGGGAAAGTCAGAAGTTGAGCAGTTCAGCTCAAAGTCAATTGGACATGAATTTTTCTCGCGAG
AGGATTTCCAATGGTTACAACCGTTTGGCGGTTCCTCGTTCGATTCAAGCGCCAGAAGATTTGACGCTTCATTTTGATAA
GGCAGGTGGTAATTCATCGCTCGGAAAGATTGTCTTTCAGACAAAAAAGCAGACAGTTACGTATCAATTATATCTAGGAA
ATGGAAAATTTAAGAAAACAACGCGTTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A4U9Y4F2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus gordonii str. Challis substr. CH1	64.444	95.07	0.613
comGD/cglD	Streptococcus mitis NCTC 12261	57.692	91.549	0.528
comGD/cglD	Streptococcus mitis SK321	56.693	89.437	0.507
comGD/cglD	Streptococcus pneumoniae Rx1	56.693	89.437	0.507
comGD/cglD	Streptococcus pneumoniae D39	56.693	89.437	0.507
comGD/cglD	Streptococcus pneumoniae R6	56.693	89.437	0.507
comGD/cglD	Streptococcus pneumoniae TIGR4	55.906	89.437	0.5
comYD	Streptococcus mutans UA140	53.846	91.549	0.493
comYD	Streptococcus mutans UA159	53.846	91.549	0.493