Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EL087_RS01010 Genome accession   NZ_LR134288
Coordinates   190791..191084 (+) Length   97 a.a.
NCBI ID   WP_126406234.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC11169     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 185791..196084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS00975 (NCTC11169_00190) - 185849..186208 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  EL087_RS00980 (NCTC11169_00191) glnA 186246..187592 (+) 1347 WP_106079126.1 type I glutamate--ammonia ligase -
  EL087_RS00985 (NCTC11169_00192) - 187777..188142 (+) 366 WP_126406228.1 DUF1033 family protein -
  EL087_RS00990 (NCTC11169_00193) comYA 188212..189153 (+) 942 WP_126406231.1 competence type IV pilus ATPase ComGA Machinery gene
  EL087_RS00995 (NCTC11169_00194) comYB 189095..190117 (+) 1023 WP_182465780.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL087_RS01000 (NCTC11169_00195) comYC 190114..190431 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  EL087_RS01005 (NCTC11169_00196) comYD 190391..190819 (+) 429 WP_037566697.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL087_RS01010 (NCTC11169_00197) comGE/cglE 190791..191084 (+) 294 WP_126406234.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL087_RS01015 (NCTC11169_00198) comGF/cglF 191068..191505 (+) 438 WP_049513212.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL087_RS01020 (NCTC11169_00199) comGG 191486..191812 (+) 327 WP_269470973.1 competence type IV pilus minor pilin ComGG -
  EL087_RS01025 (NCTC11169_00200) comYH 191884..192837 (+) 954 WP_003039058.1 class I SAM-dependent methyltransferase Machinery gene
  EL087_RS01030 (NCTC11169_00201) - 192884..194083 (+) 1200 WP_126406237.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10940.90 Da        Isoelectric Point: 10.2691

>NTDB_id=1120234 EL087_RS01010 WP_126406234.1 190791..191084(+) (comGE/cglE) [Streptococcus milleri strain NCTC11169]
MENLRKQRVRGTILLEALLALAVFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQIKQSHLTMNGIEVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1120234 EL087_RS01010 WP_126406234.1 190791..191084(+) (comGE/cglE) [Streptococcus milleri strain NCTC11169]
ATGGAAAATTTAAGAAAACAACGCGTTAGAGGAACAATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGATAAAGCAAAGCCATTTGACAATGAACGGTATTGAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

54.348

94.845

0.515
  comGE/cglE Streptococcus pneumoniae D39

54.348

94.845

0.515
  comGE/cglE Streptococcus pneumoniae R6

54.348

94.845

0.515
  comGE/cglE Streptococcus pneumoniae TIGR4

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis NCTC 12261

53.261

94.845

0.505
  comGE/cglE Streptococcus mitis SK321

53.261

94.845

0.505
  comYE Streptococcus mutans UA140

42.424

100

0.433
  comYE Streptococcus mutans UA159

42.424

100

0.433

Multiple sequence alignment