Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EL078_RS00690 Genome accession   NZ_LR134282
Coordinates   102082..103023 (+) Length   313 a.a.
NCBI ID   WP_027968018.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97082..108023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS00680 (NCTC8140_00135) rpoC 97839..101477 (+) 3639 WP_024344490.1 DNA-directed RNA polymerase subunit beta' -
  EL078_RS00685 (NCTC8140_00136) - 101645..102013 (+) 369 WP_021141429.1 DUF1033 family protein -
  EL078_RS00690 (NCTC8140_00137) comYA 102082..103023 (+) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  EL078_RS00695 (NCTC8140_00138) comYB 102947..103990 (+) 1044 WP_164554342.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL078_RS00700 (NCTC8140_00139) comYC 103990..104292 (+) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  EL078_RS00705 (NCTC8140_00140) comGD 104267..104707 (+) 441 WP_126437530.1 competence type IV pilus minor pilin ComGD -
  EL078_RS00710 (NCTC8140_00141) comGE 104661..104954 (+) 294 WP_039697664.1 competence type IV pilus minor pilin ComGE -
  EL078_RS00715 (NCTC8140_00142) comYF 104938..105375 (+) 438 WP_126437531.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL078_RS00720 (NCTC8140_00143) comGG 105362..105697 (+) 336 WP_003067902.1 competence type IV pilus minor pilin ComGG -
  EL078_RS00725 (NCTC8140_00144) comYH 105751..106707 (+) 957 WP_024344497.1 class I SAM-dependent methyltransferase Machinery gene
  EL078_RS00730 (NCTC8140_00145) - 106761..107960 (+) 1200 WP_045798327.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35736.86 Da        Isoelectric Point: 5.7732

>NTDB_id=1119949 EL078_RS00690 WP_027968018.1 102082..103023(+) (comYA) [Streptococcus equinus strain NCTC8140]
MIQEKAKQLIRDAVEKNAQDIYIIPKAENYEIYQRIGEKRQFIQEVATDEMTSLISHFKFVAGMNVGEKRRSQLGSCDYA
FADDEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMRNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPGK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIVYQRLIGGGGVVDFAKRDFEQYPPTRWNEQIDSLARDGHISFEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1119949 EL078_RS00690 WP_027968018.1 102082..103023(+) (comYA) [Streptococcus equinus strain NCTC8140]
ATGATTCAGGAAAAAGCAAAGCAGCTCATTAGAGATGCGGTTGAAAAGAATGCTCAGGATATCTATATTATTCCAAAGGC
AGAAAACTATGAGATTTATCAACGAATTGGTGAGAAACGTCAGTTTATTCAAGAAGTTGCTACTGATGAAATGACAAGCT
TGATTAGTCACTTTAAATTTGTAGCTGGGATGAATGTTGGTGAAAAGCGTCGTAGTCAGCTTGGTTCTTGTGACTATGCT
TTTGCAGATGATGAGGAGATTTCACTGCGCTTGTCTAGTGTGGGTGATTATCGTGGGCGTGAAAGTCTGGTCATTAGGCT
CCTTTATTCAGGTCGTCATGATTTGCAGTATTGGTTTGATGGAATGAGAAACATTTTAGAGGCTATTGACAGTAGGGGAC
TTTACCTTTTTTCCGGTCCGGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTAGTTCGTGAAAAATTTCCTGGAAAG
CAGGTGATTACGATTGAAGACCCTGTTGAGATTAAGCAGGACAATATGTTGCAATTGCAGTTGAATGATGAAATCGGGAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGAGTCCTTGTTTTTTCAACCATTCATGCGAAAAGTATTCCCGGTGTT
TATGCTAGGTTATTAGAATTGGGTGTTAGTAGGCAGGAACTTGAAAATAGCTTGCGCGCTATTGTTTATCAACGATTAAT
TGGTGGTGGAGGTGTAGTTGATTTTGCCAAAAGAGATTTTGAGCAGTATCCCCCAACAAGGTGGAATGAGCAAATTGATA
GCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.042

0.681
  comYA Streptococcus gordonii str. Challis substr. CH1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.103

99.681

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

42.701

87.54

0.374

Multiple sequence alignment