Detailed information NTG1119734

Bioinformatically predicted

Overview

• Name: comGA/cglA
• Type: Machinery gene
• Locus tag: EL077_RS00690
• Genome accession: NZ_LR134273
• Coordinates: 118068..119006 (+)
• Length: 312 a.a.
• NCBI ID: WP_126436208.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. equi strain NCTC12091
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113068..124006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL077_RS00675 (NCTC12091_00134)	-	113431..114663 (+)	1233	WP_014622136.1	hypothetical protein	-
EL077_RS00680 (NCTC12091_00135)	-	115236..117239 (+)	2004	WP_126436206.1	DUF1430 domain-containing protein	-
EL077_RS00685	-	117241..117912 (+)	672	Protein_101	ATP-binding cassette domain-containing protein	-
EL077_RS00690 (NCTC12091_00138)	comGA/cglA	118068..119006 (+)	939	WP_126436208.1	competence type IV pilus ATPase ComGA	Machinery gene
EL077_RS00695 (NCTC12091_00139)	comYB	118939..119973 (+)	1035	WP_337660760.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL077_RS00700 (NCTC12091_00140)	comGC/cglC	119974..120297 (+)	324	WP_014622142.1	competence type IV pilus major pilin ComGC	Machinery gene
EL077_RS00705 (NCTC12091_00141)	comGD	120275..120700 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
EL077_RS00710 (NCTC12091_00142)	comGE	120705..120947 (+)	243	WP_012677236.1	competence type IV pilus minor pilin ComGE	-
EL077_RS00715 (NCTC12091_00143)	comYF	120934..121368 (+)	435	WP_012677237.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL077_RS00720 (NCTC12091_00144)	comGG	121346..121708 (+)	363	WP_037580629.1	competence type IV pilus minor pilin ComGG	-
EL077_RS00725 (NCTC12091_00145)	comYH	121770..122723 (+)	954	WP_037580627.1	class I SAM-dependent methyltransferase	Machinery gene
EL077_RS00730 (NCTC12091_00146)	-	122783..123985 (+)	1203	WP_126436211.1	acetate kinase	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35396.62 Da
• Isoelectric Point: 7.1375

>NTDB_id=1119734 EL077_RS00690 WP_126436208.1 118068..119006(+) (comGA/cglA) [Streptococcus equi subsp. equi strain NCTC12091]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDDTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFNGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ

Nucleotide

• Length: 939 bp

>NTDB_id=1119734 EL077_RS00690 WP_126436208.1 118068..119006(+) (comGA/cglA) [Streptococcus equi subsp. equi strain NCTC12091]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGATAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGTCAGCTCGGTGCTTGTGACTACGAC
CTTGATGACACTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTAGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTAATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCAGTCGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGATAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCACAAAAGGAATTTGAACATCATCAAGCCAACCGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-264)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	67.419	99.359	0.67
comYA	Streptococcus mutans UA140	63.344	99.679	0.631
comYA	Streptococcus mutans UA159	63.344	99.679	0.631
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	61.613	99.359	0.612
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	61.29	99.359	0.609
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	61.29	99.359	0.609
comYA	Streptococcus gordonii str. Challis substr. CH1	61.29	99.359	0.609
comGA/cglA/cilD	Streptococcus pneumoniae D39	61.29	99.359	0.609
comGA/cglA/cilD	Streptococcus pneumoniae R6	61.29	99.359	0.609
comGA	Lactococcus lactis subsp. cremoris KW2	52.09	99.679	0.519
comGA	Latilactobacillus sakei subsp. sakei 23K	40.909	91.667	0.375