Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EL071_RS11725 Genome accession   NZ_LR134265
Coordinates   2238121..2239092 (-) Length   323 a.a.
NCBI ID   WP_115356969.1    Uniprot ID   A0AB38VTI3
Organism   Streptococcus agalactiae strain NCTC8184     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2233121..2244092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS11685 (NCTC8184_02330) - 2233136..2234329 (-) 1194 WP_000047534.1 acetate kinase -
  EL071_RS11690 (NCTC8184_02331) comYH 2234361..2235335 (-) 975 WP_001008571.1 class I SAM-dependent methyltransferase Machinery gene
  EL071_RS11695 (NCTC8184_02332) comGG 2235450..2235821 (-) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG -
  EL071_RS11700 (NCTC8184_02333) comGF 2235799..2236245 (-) 447 WP_115356966.1 competence type IV pilus minor pilin ComGF -
  EL071_RS11705 (NCTC8184_02334) comGE 2236199..2236498 (-) 300 WP_038406052.1 competence type IV pilus minor pilin ComGE -
  EL071_RS11710 (NCTC8184_02335) comYD 2236470..2236883 (-) 414 WP_115356967.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL071_RS11715 (NCTC8184_02336) comGC/cglC 2236858..2237187 (-) 330 WP_115356968.1 competence type IV pilus major pilin ComGC Machinery gene
  EL071_RS11720 (NCTC8184_02337) comYB 2237184..2238227 (-) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL071_RS11725 (NCTC8184_02338) comYA 2238121..2239092 (-) 972 WP_115356969.1 competence type IV pilus ATPase ComGA Machinery gene
  EL071_RS11735 (NCTC8184_02339) - 2239264..2239629 (-) 366 WP_115356970.1 DUF1033 family protein -
  EL071_RS11740 (NCTC8184_02340) rpoC 2239743..2243393 (-) 3651 WP_115356971.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36714.16 Da        Isoelectric Point: 7.1728

>NTDB_id=1119537 EL071_RS11725 WP_115356969.1 2238121..2239092(-) (comYA) [Streptococcus agalactiae strain NCTC8184]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSGGRLVSLRLSSVGDYRGQESLVIRTLYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETSNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=1119537 EL071_RS11725 WP_115356969.1 2238121..2239092(-) (comYA) [Streptococcus agalactiae strain NCTC8184]
ATGGTTCAATCATTAGCAAAGCACGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGGGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAC
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTAATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAAGTAACTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.167

96.285

0.656
  comYA Streptococcus mutans UA140

68.167

96.285

0.656
  comYA Streptococcus gordonii str. Challis substr. CH1

63.636

98.762

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.701

96.285

0.604
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.736

96.285

0.594
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

95.975

0.594
  comGA Lactococcus lactis subsp. cremoris KW2

51.242

99.69

0.511

Multiple sequence alignment