Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EL071_RS11715 Genome accession   NZ_LR134265
Coordinates   2236858..2237187 (-) Length   109 a.a.
NCBI ID   WP_115356968.1    Uniprot ID   A0AB38VTL0
Organism   Streptococcus agalactiae strain NCTC8184     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2231858..2242187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS11670 (NCTC8184_02328) - 2232087..2232542 (-) 456 WP_115356965.1 hypothetical protein -
  EL071_RS11675 - 2232583..2232720 (-) 138 WP_001869149.1 hypothetical protein -
  EL071_RS11680 (NCTC8184_02329) - 2232779..2232985 (-) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  EL071_RS11685 (NCTC8184_02330) - 2233136..2234329 (-) 1194 WP_000047534.1 acetate kinase -
  EL071_RS11690 (NCTC8184_02331) comYH 2234361..2235335 (-) 975 WP_001008571.1 class I SAM-dependent methyltransferase Machinery gene
  EL071_RS11695 (NCTC8184_02332) comGG 2235450..2235821 (-) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG -
  EL071_RS11700 (NCTC8184_02333) comGF 2235799..2236245 (-) 447 WP_115356966.1 competence type IV pilus minor pilin ComGF -
  EL071_RS11705 (NCTC8184_02334) comGE 2236199..2236498 (-) 300 WP_038406052.1 competence type IV pilus minor pilin ComGE -
  EL071_RS11710 (NCTC8184_02335) comYD 2236470..2236883 (-) 414 WP_115356967.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL071_RS11715 (NCTC8184_02336) comGC/cglC 2236858..2237187 (-) 330 WP_115356968.1 competence type IV pilus major pilin ComGC Machinery gene
  EL071_RS11720 (NCTC8184_02337) comYB 2237184..2238227 (-) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL071_RS11725 (NCTC8184_02338) comYA 2238121..2239092 (-) 972 WP_115356969.1 competence type IV pilus ATPase ComGA Machinery gene
  EL071_RS11735 (NCTC8184_02339) - 2239264..2239629 (-) 366 WP_115356970.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12099.24 Da        Isoelectric Point: 10.0311

>NTDB_id=1119535 EL071_RS11715 WP_115356968.1 2236858..2237187(-) (comGC/cglC) [Streptococcus agalactiae strain NCTC8184]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISG

Nucleotide


Download         Length: 330 bp        

>NTDB_id=1119535 EL071_RS11715 WP_115356968.1 2236858..2237187(-) (comGC/cglC) [Streptococcus agalactiae strain NCTC8184]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGCTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCTGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAGGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

61.111

99.083

0.606
  comGC/cglC Streptococcus mitis SK321

60.185

99.083

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

58.333

99.083

0.578
  comGC/cglC Streptococcus pneumoniae R6

58.333

99.083

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

58.333

99.083

0.578
  comGC/cglC Streptococcus pneumoniae D39

58.333

99.083

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment