Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL071_RS11720 Genome accession   NZ_LR134265
Coordinates   2237184..2238227 (-) Length   347 a.a.
NCBI ID   WP_223297804.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC8184     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2232184..2243227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS11675 - 2232583..2232720 (-) 138 WP_001869149.1 hypothetical protein -
  EL071_RS11680 (NCTC8184_02329) - 2232779..2232985 (-) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  EL071_RS11685 (NCTC8184_02330) - 2233136..2234329 (-) 1194 WP_000047534.1 acetate kinase -
  EL071_RS11690 (NCTC8184_02331) comYH 2234361..2235335 (-) 975 WP_001008571.1 class I SAM-dependent methyltransferase Machinery gene
  EL071_RS11695 (NCTC8184_02332) comGG 2235450..2235821 (-) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG -
  EL071_RS11700 (NCTC8184_02333) comGF 2235799..2236245 (-) 447 WP_115356966.1 competence type IV pilus minor pilin ComGF -
  EL071_RS11705 (NCTC8184_02334) comGE 2236199..2236498 (-) 300 WP_038406052.1 competence type IV pilus minor pilin ComGE -
  EL071_RS11710 (NCTC8184_02335) comYD 2236470..2236883 (-) 414 WP_115356967.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL071_RS11715 (NCTC8184_02336) comGC/cglC 2236858..2237187 (-) 330 WP_115356968.1 competence type IV pilus major pilin ComGC Machinery gene
  EL071_RS11720 (NCTC8184_02337) comYB 2237184..2238227 (-) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL071_RS11725 (NCTC8184_02338) comYA 2238121..2239092 (-) 972 WP_115356969.1 competence type IV pilus ATPase ComGA Machinery gene
  EL071_RS11735 (NCTC8184_02339) - 2239264..2239629 (-) 366 WP_115356970.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40014.77 Da        Isoelectric Point: 9.9642

>NTDB_id=1119536 EL071_RS11720 WP_223297804.1 2237184..2238227(-) (comYB) [Streptococcus agalactiae strain NCTC8184]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDRMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRHYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGVELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1119536 EL071_RS11720 WP_223297804.1 2237184..2238227(-) (comYB) [Streptococcus agalactiae strain NCTC8184]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGGATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGCATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTGTTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGTCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAATTAATCCAACCCGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

62.17

98.271

0.611
  comYB Streptococcus mutans UA159

61.877

98.271

0.608
  comYB Streptococcus gordonii str. Challis substr. CH1

56.012

98.271

0.55
  comGB/cglB Streptococcus mitis NCTC 12261

54.925

96.542

0.53
  comGB/cglB Streptococcus mitis SK321

54.328

96.542

0.524
  comGB/cglB Streptococcus pneumoniae Rx1

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae D39

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae R6

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae TIGR4

53.433

96.542

0.516
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.118

0.487

Multiple sequence alignment