Detailed information NTG1116462

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: EQB47_RS10110
• Genome accession: NZ_LR129844
• Coordinates: 1835196..1836137 (-)
• Length: 313 a.a.
• NCBI ID: WP_000249552.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 180-15 isolate 180-15
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1830196..1841137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB47_RS10070	comYH	1830682..1831635 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
EQB47_RS10075	-	1831696..1832290 (-)	595	Protein_1879	class I SAM-dependent methyltransferase	-
EQB47_RS10080	comGG/cglG	1832427..1832840 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQB47_RS10085	comGF/cglF	1832818..1833279 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQB47_RS10090	comGE/cglE	1833242..1833544 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQB47_RS10095	comGD/cglD	1833507..1833911 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQB47_RS10100	comGC/cglC	1833904..1834230 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
EQB47_RS10105	comGB/cglB	1834232..1835248 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQB47_RS10110	comGA/cglA/cilD	1835196..1836137 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
EQB47_RS10115	-	1836213..1836578 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQB47_RS10120	-	1836729..1837787 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
EQB47_RS10125	nagA	1837950..1839101 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
EQB47_RS10130	-	1839254..1841071 (-)	1818	WP_001220922.1	acyltransferase family protein	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35587.57 Da
• Isoelectric Point: 6.0083

>NTDB_id=1116462 EQB47_RS10110 WP_000249552.1 1835196..1836137(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide

• Length: 942 bp

>NTDB_id=1116462 EQB47_RS10110 WP_000249552.1 1835196..1836137(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGCTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCCAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGTCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACATCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	98.403	100	0.984
comGA/cglA/cilD	Streptococcus pneumoniae D39	98.403	100	0.984
comGA/cglA/cilD	Streptococcus pneumoniae R6	98.403	100	0.984
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	98.403	100	0.984
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	96.805	100	0.968
comYA	Streptococcus gordonii str. Challis substr. CH1	77.742	99.042	0.77
comYA	Streptococcus mutans UA159	66.238	99.361	0.658
comYA	Streptococcus mutans UA140	66.238	99.361	0.658
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	62.903	99.042	0.623
comGA	Lactococcus lactis subsp. cremoris KW2	55.128	99.681	0.55
comGA	Latilactobacillus sakei subsp. sakei 23K	41.912	86.901	0.364