Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EQB47_RS10090 Genome accession   NZ_LR129844
Coordinates   1833242..1833544 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 180-15 isolate 180-15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1828242..1838544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB47_RS10060 rnpA 1828921..1829292 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQB47_RS11950 - 1829309..1829440 (-) 132 WP_000768904.1 hypothetical protein -
  EQB47_RS10065 - 1829441..1830631 (-) 1191 WP_000167765.1 acetate kinase -
  EQB47_RS10070 comYH 1830682..1831635 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  EQB47_RS10075 - 1831696..1832290 (-) 595 Protein_1879 class I SAM-dependent methyltransferase -
  EQB47_RS10080 comGG/cglG 1832427..1832840 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQB47_RS10085 comGF/cglF 1832818..1833279 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQB47_RS10090 comGE/cglE 1833242..1833544 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQB47_RS10095 comGD/cglD 1833507..1833911 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQB47_RS10100 comGC/cglC 1833904..1834230 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  EQB47_RS10105 comGB/cglB 1834232..1835248 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQB47_RS10110 comGA/cglA/cilD 1835196..1836137 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  EQB47_RS10115 - 1836213..1836578 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQB47_RS10120 - 1836729..1837787 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=1116458 EQB47_RS10090 WP_000413382.1 1833242..1833544(-) (comGE/cglE) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1116458 EQB47_RS10090 WP_000413382.1 1833242..1833544(-) (comGE/cglE) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment