Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   ACLRDL_RS01590 Genome accession   NZ_CP178387
Coordinates   323766..324881 (-) Length   371 a.a.
NCBI ID   WP_000654777.1    Uniprot ID   -
Organism   Vibrio cholerae isolate CTMA_1842     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 318766..329881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLRDL_RS01560 (ACLRDL_01560) hemF 319352..320269 (-) 918 WP_000443972.1 oxygen-dependent coproporphyrinogen oxidase -
  ACLRDL_RS01565 (ACLRDL_01565) - 320288..320845 (-) 558 WP_001926378.1 L-threonylcarbamoyladenylate synthase -
  ACLRDL_RS01570 (ACLRDL_01570) purE 321012..321497 (+) 486 WP_000215768.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  ACLRDL_RS01575 (ACLRDL_01575) - 321501..322634 (+) 1134 WP_001265389.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  ACLRDL_RS01580 (ACLRDL_01580) - 322707..323273 (-) 567 WP_000087521.1 type I DNA topoisomerase -
  ACLRDL_RS01585 (ACLRDL_01585) - 323287..323763 (-) 477 WP_000979769.1 DUF494 family protein -
  ACLRDL_RS01590 (ACLRDL_01590) dprA 323766..324881 (-) 1116 WP_000654777.1 DNA-processing protein DprA Machinery gene
  ACLRDL_RS01595 (ACLRDL_01595) - 324881..326008 (-) 1128 WP_000113385.1 LysM peptidoglycan-binding domain-containing protein -
  ACLRDL_RS01600 (ACLRDL_01600) def 326148..326657 (+) 510 WP_000115010.1 peptide deformylase -
  ACLRDL_RS01605 (ACLRDL_01605) fmt 326675..327622 (+) 948 WP_000083526.1 methionyl-tRNA formyltransferase -
  ACLRDL_RS01610 (ACLRDL_01610) rsmB 327678..328958 (+) 1281 WP_001102799.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 371 a.a.        Molecular weight: 39978.98 Da        Isoelectric Point: 7.1952

>NTDB_id=1089373 ACLRDL_RS01590 WP_000654777.1 323766..324881(-) (dprA) [Vibrio cholerae isolate CTMA_1842]
MKDQDLAAWLALCFTPKLGSKTISHLLATRLPAQLQSFTPKQWLASGLKPEQLVFLTTQAAKQAELCLQWRSAANNRYIV
TPHCPLYPRLLKEISSSPPILFIEGIWEAVHDPAVAIVGSRNASVDGRQIARQFATELAQSGLVVTSGLALGIDGYAHDG
ALQAQGQTVAVLGSGLAQVYPKQHQGLAERIMAQGALVSEFAPHTPPKADHFPRRNRIISGLSLGVVVVEAAEKSGSLIT
ARYAAEQGREVFVVPGSIFNAASQGSNQLIRQGACLVQSVQQIHQELKNALTWSLSEQVPYQATLFSAVQGDEELPFPEL
LANVGIEATPIDILASRTQIPVQDIMMQLLELELLGHVVAVPGGYIRKGRG

Nucleotide


Download         Length: 1116 bp        

>NTDB_id=1089373 ACLRDL_RS01590 WP_000654777.1 323766..324881(-) (dprA) [Vibrio cholerae isolate CTMA_1842]
ATGAAAGATCAGGATTTAGCGGCATGGTTGGCGCTCTGTTTTACTCCTAAACTAGGCAGCAAAACCATTTCTCACCTGCT
TGCGACCCGTTTGCCAGCCCAGTTGCAAAGTTTTACGCCTAAGCAATGGTTGGCCAGCGGGCTTAAGCCCGAACAACTGG
TGTTTTTAACCACTCAAGCGGCTAAGCAAGCCGAGCTGTGTTTGCAATGGCGATCAGCAGCCAATAACCGCTATATCGTC
ACTCCTCATTGCCCGCTTTACCCTCGTTTATTGAAAGAGATTAGCTCATCGCCTCCCATCCTGTTTATTGAAGGTATATG
GGAAGCGGTGCATGACCCTGCGGTGGCTATCGTCGGTAGCCGCAATGCCAGTGTTGATGGGCGGCAGATAGCTCGCCAGT
TTGCCACTGAGCTCGCGCAGTCGGGTTTAGTGGTCACCAGTGGTTTAGCGCTTGGTATAGACGGCTATGCGCACGATGGC
GCTTTGCAAGCACAAGGGCAAACCGTGGCAGTATTAGGCTCAGGGCTGGCGCAGGTTTACCCCAAACAGCATCAAGGATT
AGCGGAGCGAATCATGGCCCAAGGGGCCTTGGTTTCTGAGTTTGCCCCTCACACACCGCCTAAAGCCGATCACTTTCCGC
GCCGTAACCGAATTATCAGCGGCTTATCGTTGGGCGTTGTGGTGGTAGAAGCTGCGGAGAAAAGCGGCTCACTCATCACT
GCGCGCTACGCCGCTGAGCAAGGGCGTGAGGTCTTTGTGGTTCCCGGCTCGATTTTTAATGCCGCCAGCCAAGGTAGCAA
TCAATTGATTCGTCAAGGCGCTTGTTTGGTGCAAAGTGTGCAACAAATTCATCAAGAGCTCAAAAATGCGCTGACTTGGT
CACTCTCTGAACAAGTTCCTTATCAAGCAACACTTTTTTCTGCTGTACAGGGCGATGAAGAATTGCCATTTCCCGAGCTG
TTAGCTAACGTAGGAATAGAAGCTACACCTATTGATATTCTCGCAAGCCGGACCCAGATACCGGTGCAAGATATCATGAT
GCAGCTCTTGGAGCTTGAGCTCCTTGGGCATGTGGTTGCAGTACCTGGTGGCTATATTAGAAAGGGGAGAGGCTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(77-278)

DprA winged helix domain (DprA_WH)

(319-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae strain A1552

98.383

100

0.984
  dprA Vibrio campbellii strain DS40M4

58.108

99.73

0.58
  dprA Legionella pneumophila strain ERS1305867

43.583

100

0.439
  dprA Glaesserella parasuis strain SC1401

43.351

100

0.439
  dprA Neisseria meningitidis strain C311

37.594

100

0.404
  dprA Neisseria meningitidis MC58

37.594

100

0.404
  dprA Neisseria gonorrhoeae strain FA1090

36.776

100

0.394
  dprA Acinetobacter baumannii D1279779

43.505

89.218

0.388
  dprA Acinetobacter baumannii strain A118

43.202

89.218

0.385
  dprA Neisseria gonorrhoeae MS11

35.949

100

0.383
  dprA Acinetobacter baylyi ADP1

42.042

89.757

0.377
  dprA Haemophilus influenzae Rd KW20

48.387

75.202

0.364

Multiple sequence alignment