Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ACKWPP_RS00750 Genome accession   NZ_CP176418
Coordinates   119304..120254 (+) Length   316 a.a.
NCBI ID   WP_023369082.1    Uniprot ID   -
Organism   Streptococcus suis strain KKAHC02     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 114304..125254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS00740 (ACKWPP_00740) - 117868..118233 (+) 366 WP_409374001.1 DUF1033 family protein -
  ACKWPP_RS00745 (ACKWPP_00745) - 118268..119218 (-) 951 WP_409374002.1 S66 peptidase family protein -
  ACKWPP_RS00750 (ACKWPP_00750) comYA 119304..120254 (+) 951 WP_023369082.1 competence type IV pilus ATPase ComGA Machinery gene
  ACKWPP_RS00755 (ACKWPP_00755) comYB 120166..121203 (+) 1038 WP_044680150.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACKWPP_RS00760 (ACKWPP_00760) comYC 121205..121486 (+) 282 WP_044680148.1 competence type IV pilus major pilin ComGC Machinery gene
  ACKWPP_RS00765 (ACKWPP_00765) comGD 121467..121874 (+) 408 WP_044762031.1 competence type IV pilus minor pilin ComGD -
  ACKWPP_RS00770 (ACKWPP_00770) comYE 121846..122139 (+) 294 WP_024385126.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACKWPP_RS00775 (ACKWPP_00775) comGF/cglF 122126..122560 (+) 435 WP_074414675.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACKWPP_RS00780 (ACKWPP_00780) comGG 122538..122948 (+) 411 WP_409374003.1 competence type IV pilus minor pilin ComGG -
  ACKWPP_RS00785 (ACKWPP_00785) comYH 123005..123958 (+) 954 WP_002936545.1 class I SAM-dependent methyltransferase Machinery gene
  ACKWPP_RS00790 (ACKWPP_00790) - 124008..125195 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35426.29 Da        Isoelectric Point: 5.4744

>NTDB_id=1080045 ACKWPP_RS00750 WP_023369082.1 119304..120254(+) (comYA) [Streptococcus suis strain KKAHC02]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=1080045 ACKWPP_RS00750 WP_023369082.1 119304..120254(+) (comYA) [Streptococcus suis strain KKAHC02]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTCATGTATCATCTTGCCAGGCTGAAGTTTCCAGACAAGCAA
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGATAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATTATCGGTGAAATTCGGGATGCGGAAACGG
CACGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTCCATGCAAGGTCTATTTCAGGTGTCTAC
GCCCGTATGTTGGAATTGGGTGTTAGTCCTGAGGAGCTAAACAATGCCCTTCAAGGCATTGCCTATCAACGATTGATTGG
GGGAGGAGGTGTAGTGGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361

Multiple sequence alignment