Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ACKWPP_RS00755 Genome accession   NZ_CP176418
Coordinates   120166..121203 (+) Length   345 a.a.
NCBI ID   WP_044680150.1    Uniprot ID   -
Organism   Streptococcus suis strain KKAHC02     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115166..126203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS00740 (ACKWPP_00740) - 117868..118233 (+) 366 WP_409374001.1 DUF1033 family protein -
  ACKWPP_RS00745 (ACKWPP_00745) - 118268..119218 (-) 951 WP_409374002.1 S66 peptidase family protein -
  ACKWPP_RS00750 (ACKWPP_00750) comYA 119304..120254 (+) 951 WP_023369082.1 competence type IV pilus ATPase ComGA Machinery gene
  ACKWPP_RS00755 (ACKWPP_00755) comYB 120166..121203 (+) 1038 WP_044680150.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACKWPP_RS00760 (ACKWPP_00760) comYC 121205..121486 (+) 282 WP_044680148.1 competence type IV pilus major pilin ComGC Machinery gene
  ACKWPP_RS00765 (ACKWPP_00765) comGD 121467..121874 (+) 408 WP_044762031.1 competence type IV pilus minor pilin ComGD -
  ACKWPP_RS00770 (ACKWPP_00770) comYE 121846..122139 (+) 294 WP_024385126.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACKWPP_RS00775 (ACKWPP_00775) comGF/cglF 122126..122560 (+) 435 WP_074414675.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACKWPP_RS00780 (ACKWPP_00780) comGG 122538..122948 (+) 411 WP_409374003.1 competence type IV pilus minor pilin ComGG -
  ACKWPP_RS00785 (ACKWPP_00785) comYH 123005..123958 (+) 954 WP_002936545.1 class I SAM-dependent methyltransferase Machinery gene
  ACKWPP_RS00790 (ACKWPP_00790) - 124008..125195 (+) 1188 WP_014637319.1 acetate kinase -
  ACKWPP_RS00795 (ACKWPP_00795) - 125510..126061 (+) 552 WP_141587968.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38993.03 Da        Isoelectric Point: 9.3364

>NTDB_id=1080046 ACKWPP_RS00755 WP_044680150.1 120166..121203(+) (comYB) [Streptococcus suis strain KKAHC02]
MRKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKVFSCLVSLPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVALMQS
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=1080046 ACKWPP_RS00755 WP_044680150.1 120166..121203(+) (comYB) [Streptococcus suis strain KKAHC02]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAACTGTTTAATAATCTCTTTGCCAGTGGTTTTCATCTGGGAGAGATTGTCGATTTTCTTAAGC
GTAGTCAGCTTTTGGCAGACCCATATACACAAGTTTTATCCGATGGTCTTCTTGCAGGCAAACCTTTTTCAAGTTTGCTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAGGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTTAGCAAGGTTCGTAAAAAATTGATTGAGGTGGCGACCTATCCAGTTATCTTGC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCTGCGACCATG
TTAATTAACCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGTATCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGCCTTGATGCAATCG
CAGCAATCGCAGCTCTTTCGGGAGATTGGCCAAGACTTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
CAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGGAGCGAGT
TGACAGTCTATGCAGCTGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTT
TTTCTCTTTGTGGCTTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.158

99.13

0.626
  comGB/cglB Streptococcus mitis NCTC 12261

60.299

97.101

0.586
  comGB/cglB Streptococcus mitis SK321

60

97.101

0.583
  comYB Streptococcus mutans UA140

58.651

98.841

0.58
  comYB Streptococcus mutans UA159

58.651

98.841

0.58
  comGB/cglB Streptococcus pneumoniae Rx1

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae D39

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae TIGR4

59.701

97.101

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

97.681

0.499

Multiple sequence alignment