Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DK43_RS00670 Genome accession   NZ_CP007573
Coordinates   132544..133812 (+) Length   422 a.a.
NCBI ID   WP_022525214.1    Uniprot ID   A0ABD7NGJ4
Organism   Streptococcus anginosus strain SA1     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 127544..138812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS00645 (DK43_00670) hexB 127916..129862 (+) 1947 WP_037593386.1 DNA mismatch repair endonuclease MutL Machinery gene
  DK43_RS00650 (DK43_00675) ruvA 129996..130586 (+) 591 WP_003027779.1 Holliday junction branch migration protein RuvA Machinery gene
  DK43_RS00655 (DK43_00680) - 130596..131150 (+) 555 WP_003027778.1 DNA-3-methyladenine glycosylase I -
  DK43_RS00660 (DK43_00685) - 131155..131813 (+) 659 Protein_130 lysostaphin resistance A-like protein -
  DK43_RS00665 (DK43_00690) - 131864..132274 (-) 411 WP_003027775.1 helix-turn-helix transcriptional regulator -
  DK43_RS00670 (DK43_00700) cinA 132544..133812 (+) 1269 WP_022525214.1 competence/damage-inducible protein A Machinery gene
  DK43_RS00675 (DK43_00705) recA 133860..135005 (+) 1146 WP_003027772.1 recombinase RecA -
  DK43_RS00680 (DK43_00710) spx 135092..135490 (+) 399 WP_003027770.1 transcriptional regulator Spx -
  DK43_RS00685 (DK43_00715) - 135574..136143 (+) 570 WP_003027769.1 SP0191 family lipoprotein -
  DK43_RS00690 (DK43_00720) - 136248..136805 (+) 558 WP_022525213.1 SP0191 family lipoprotein -
  DK43_RS00695 (DK43_00725) - 136928..137194 (+) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  DK43_RS00700 (DK43_00730) ruvX 137194..137613 (+) 420 WP_003027766.1 Holliday junction resolvase RuvX -
  DK43_RS00705 (DK43_00735) - 137631..137942 (+) 312 WP_003027765.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45742.26 Da        Isoelectric Point: 6.5228

>NTDB_id=106091 DK43_RS00670 WP_022525214.1 132544..133812(+) (cinA) [Streptococcus anginosus strain SA1]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLIILTGGLGPTEDDLTKQT
LSKFLNRRLVFDRMATEKLDRFFASRPDYVRTPNNERQAQIVEGSTSLQNETGLAVGGVIEVSGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDTQTDPTIAPYAKTGEVTLRLSTKATSQKEADVKFTRLEKKI
LAVQTFEKQHLADLFYAYGDDNSLGQTAFELLRRAGKTVTAAESLTAGLFQATLANFAGASNVFSGGFVTYSMEEKSRML
GIPLADLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLSKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=106091 DK43_RS00670 WP_022525214.1 132544..133812(+) (cinA) [Streptococcus anginosus strain SA1]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAAATTGTCAATACAAACGCCCAATTTTTATCTGA
AAAATTAGCGAGTCTGGGAGTAGATGTGTATTTCCAAACAGCGGTCGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATCGCTCGAAATCGTAGTAATTTGATCATCTTAACTGGAGGATTAGGTCCAACAGAAGATGACTTGACTAAGCAGACT
TTGTCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGATCGCTTCTTCGCAAGTCGACC
GGACTATGTGCGAACACCCAATAATGAGCGACAAGCTCAGATAGTGGAAGGCTCGACCTCTCTCCAAAACGAAACCGGAC
TTGCAGTGGGGGGCGTGATTGAAGTCAGTGGGGTGACTTATGTCGTTCTGCCTGGACCGCCTAGTGAATTAAAACCTATG
GTAAATAATGAGCTGGTTCCGCTCTTAGCAACTGGTCAAAAATTGTATTCAAGAGTTTTGCGTTTCTTTGGTATTGGTGA
AAGTCAATTAGTAACCCTTTTAGGGGATTTAATTGATACTCAAACGGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AAGTAACTTTGCGATTGTCCACCAAGGCTACTAGTCAAAAGGAAGCGGATGTTAAGTTTACTCGTTTAGAAAAGAAAATT
TTAGCAGTACAAACTTTTGAGAAACAACATTTAGCTGATCTTTTCTACGCTTATGGAGATGATAATTCTCTGGGACAAAC
AGCTTTTGAACTGCTGAGAAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTTTTTCAAGCAACTT
TAGCAAACTTTGCTGGTGCCTCCAATGTTTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GGCATTCCCTTGGCAGACTTGGAAAAGCATGGGGTGGTTTCAGCTTTTACAGCAGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGATAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGCTTAGCAACCACAGAGGATGTTCAGTCTATTAAGGTTAATATTGCGGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTGCGAAAAACTTTATCAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterProScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0ABD7NGJ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.145

98.341

0.749
  cinA Streptococcus mitis NCTC 12261

75.181

98.341

0.739
  cinA Streptococcus pneumoniae R36A

74.94

98.341

0.737
  cinA Streptococcus pneumoniae Rx1

74.94

98.341

0.737
  cinA Streptococcus pneumoniae R6

74.94

98.341

0.737
  cinA Streptococcus pneumoniae TIGR4

74.94

98.341

0.737
  cinA Streptococcus pneumoniae D39

74.699

98.341

0.735
  cinA Streptococcus mutans UA159

72.577

100

0.727
  cinA Streptococcus suis isolate S10

56.01

98.578

0.552
  cinA Bacillus subtilis subsp. subtilis str. 168

45.714

99.526

0.455