Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   ACFMSI_RS07670 Genome accession   NZ_CP170579
Coordinates   1565973..1566284 (+) Length   103 a.a.
NCBI ID   WP_000472256.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JB2E56     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1560973..1571284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFMSI_RS07640 (ACFMSI_07640) - 1561756..1561959 (+) 204 WP_000087559.1 YqgQ family protein -
  ACFMSI_RS07645 (ACFMSI_07645) - 1561956..1562942 (+) 987 WP_000161315.1 ROK family glucokinase -
  ACFMSI_RS07650 (ACFMSI_07650) - 1562942..1563271 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ACFMSI_RS07655 (ACFMSI_07655) - 1563268..1563891 (+) 624 WP_113587809.1 MBL fold metallo-hydrolase -
  ACFMSI_RS07660 (ACFMSI_07660) comGA 1563943..1564917 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  ACFMSI_RS07665 (ACFMSI_07665) comGB 1564889..1565959 (+) 1071 WP_000776425.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACFMSI_RS07670 (ACFMSI_07670) comGC 1565973..1566284 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  ACFMSI_RS07675 (ACFMSI_07675) comGD 1566262..1566708 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACFMSI_RS07680 (ACFMSI_07680) comGE 1566695..1566994 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  ACFMSI_RS07685 (ACFMSI_07685) - 1566912..1567337 (+) 426 Protein_1480 competence type IV pilus minor pilin ComGF -
  ACFMSI_RS07690 (ACFMSI_07690) - 1567433..1568605 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  ACFMSI_RS07695 (ACFMSI_07695) - 1568655..1568741 (+) 87 Protein_1482 type IV pilus minor pilin ComGF family protein -
  ACFMSI_RS07700 (ACFMSI_07700) - 1568838..1568984 (+) 147 WP_001789879.1 hypothetical protein -
  ACFMSI_RS07705 (ACFMSI_07705) - 1568974..1569498 (+) 525 WP_001015120.1 shikimate kinase -
  ACFMSI_RS07710 (ACFMSI_07710) gcvT 1569657..1570748 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence


Protein


Download         Length: 103 a.a.        Molecular weight: 11315.36 Da        Isoelectric Point: 8.5268

>NTDB_id=1058133 ACFMSI_RS07670 WP_000472256.1 1565973..1566284(+) (comGC) [Staphylococcus aureus strain JB2E56]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=1058133 ACFMSI_RS07670 WP_000472256.1 1565973..1566284(+) (comGC) [Staphylococcus aureus strain JB2E56]
ATGTTTAAATTTCTAAAAAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTATTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

100

100

1

  comGC Staphylococcus aureus N315

100

100

1

  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456

  comGC/cglC Streptococcus mitis SK321

51.163

83.495

0.427

  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427

  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408

  comYC Streptococcus suis isolate S10

50

75.728

0.379

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369


Multiple sequence alignment