Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbB/cilA   Type   Machinery gene
Locus tag   ACE2AN_RS08750 Genome accession   NZ_CP169564
Coordinates   1735038..1735433 (-) Length   131 a.a.
NCBI ID   WP_000282467.1    Uniprot ID   A0A098Z0L0
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1731482..1753716 1735038..1735433 within 0


Gene organization within MGE regions


Location: 1731482..1753716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS08735 - 1731518..1732747 (+) 1230 WP_279514573.1 ISL3 family transposase -
  ACE2AN_RS08740 groL 1732846..1734468 (-) 1623 WP_000031585.1 chaperonin GroEL -
  ACE2AN_RS08745 groES 1734484..1734768 (-) 285 WP_000917330.1 co-chaperone GroES -
  ACE2AN_RS08750 ssbB/cilA 1735038..1735433 (-) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  ACE2AN_RS08755 - 1735510..1736271 (-) 762 WP_001107755.1 SDR family NAD(P)-dependent oxidoreductase -
  ACE2AN_RS08760 ytpR 1736304..1736930 (-) 627 WP_000578309.1 YtpR family tRNA-binding protein -
  ACE2AN_RS08765 - 1736946..1737263 (-) 318 WP_000615767.1 thioredoxin family protein -
  ACE2AN_RS08770 - 1737260..1737559 (-) 300 WP_001013974.1 DUF4651 domain-containing protein -
  ACE2AN_RS08775 - 1737757..1737954 (-) 198 Protein_1715 N-acetylmuramoyl-L-alanine amidase family protein -
  ACE2AN_RS08780 - 1738196..1738870 (-) 675 WP_044813801.1 membrane protein -
  ACE2AN_RS08785 - 1738875..1739321 (-) 447 WP_044813800.1 LytTR family DNA-binding domain-containing protein -
  ACE2AN_RS08790 - 1739435..1739938 (-) 504 WP_000800923.1 phosphatase PAP2 family protein -
  ACE2AN_RS08795 - 1739935..1740297 (-) 363 WP_000078805.1 DUF2200 domain-containing protein -
  ACE2AN_RS08800 rcrQ 1740363..1741394 (-) 1032 WP_000506425.1 ABC transporter ATP-binding protein Regulator
  ACE2AN_RS08805 - 1741401..1742222 (-) 822 Protein_1721 ABC transporter permease -
  ACE2AN_RS08810 - 1742239..1742710 (-) 472 Protein_1722 MarR family winged helix-turn-helix transcriptional regulator -
  ACE2AN_RS08815 - 1742834..1743550 (-) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  ACE2AN_RS08820 ply 1744431..1745846 (-) 1416 WP_001284361.1 cholesterol-dependent cytolysin pneumolysin -
  ACE2AN_RS08825 - 1745857..1746267 (-) 411 WP_000595758.1 hypothetical protein -
  ACE2AN_RS08830 - 1746260..1746868 (-) 609 WP_000083614.1 hypothetical protein -
  ACE2AN_RS08835 - 1746881..1747339 (-) 459 WP_000186955.1 DUF4231 domain-containing protein -
  ACE2AN_RS08840 - 1747464..1747863 (+) 400 Protein_1728 transposase family protein -
  ACE2AN_RS08845 - 1748349..1749182 (+) 834 WP_050103383.1 glycerophosphodiester phosphodiesterase family protein -
  ACE2AN_RS08850 - 1749225..1750286 (+) 1062 WP_000475761.1 extracellular solute-binding protein -
  ACE2AN_RS08855 - 1750303..1751307 (+) 1005 WP_000627599.1 ABC transporter ATP-binding protein -
  ACE2AN_RS08860 - 1751319..1753013 (+) 1695 WP_001232286.1 iron ABC transporter permease -
  ACE2AN_RS08865 - 1753015..1753716 (+) 702 WP_001054457.1 MgtC/SapB family protein -

Sequence

Protein


Download         Length: 131 a.a.        Molecular weight: 14925.89 Da        Isoelectric Point: 5.9409

>NTDB_id=1052201 ACE2AN_RS08750 WP_000282467.1 1735038..1735433(-) (ssbB/cilA) [Streptococcus pneumoniae strain 6_2F1]
MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNMVLWGRLAETLASYATKGSLISVDGELRTR
RFEKNGQMNYVTEVLVTGFQLLESRAQRAMRENNAGQDLADLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=1052201 ACE2AN_RS08750 WP_000282467.1 1735038..1735433(-) (ssbB/cilA) [Streptococcus pneumoniae strain 6_2F1]
ATGTATAATAAAGTTATCATGATTGGGCGTTTAACGTCTACACCAGAATTGCACAAAACCAACAATGACAAGTCGGTAGC
GCGAGCAACTATCGCTGTCAACCGTCGTTACAAAGACCAAAACGGTGAACGTGAAGCTGATTTTGTCAATATGGTCCTAT
GGGGCAGACTAGCAGAAACTTTGGCAAGCTACGCAACCAAAGGTAGTCTCATTTCCGTTGATGGAGAATTGCGTACCCGT
CGCTTTGAGAAAAATGGTCAGATGAACTATGTAACCGAAGTCCTTGTAACAGGATTCCAACTCTTGGAAAGTCGTGCTCA
ACGTGCCATGCGTGAAAATAATGCAGGCCAAGATTTGGCAGATTTGGTCTTGGAAGAGGAAGAATTGCCATTTTAA

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(3-101)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z0L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbB/cilA Streptococcus pneumoniae D39

100

100

1
  ssbB/cilA Streptococcus pneumoniae Rx1

100

100

1
  ssbB/cilA Streptococcus pneumoniae R6

100

100

1
  ssbB/cilA Streptococcus pneumoniae TIGR4

99.237

100

0.992
  ssbB/cilA Streptococcus mitis SK321

98.473

100

0.985
  ssbB/cilA Streptococcus mitis NCTC 12261

98.473

100

0.985
  ssbA Streptococcus mutans UA159

74.809

100

0.748
  ssbB Streptococcus sobrinus strain NIDR 6715-7

70.229

100

0.702
  ssbB Lactococcus lactis subsp. cremoris KW2

59.821

85.496

0.511
  ssbA Bacillus subtilis subsp. subtilis str. 168

50.943

80.916

0.412
  ssb Latilactobacillus sakei subsp. sakei 23K

46.903

86.26

0.405

Multiple sequence alignment