Detailed information    

insolico Bioinformatically predicted

Overview

Name   rcrQ   Type   Regulator
Locus tag   ACE2AN_RS08800 Genome accession   NZ_CP169564
Coordinates   1740363..1741394 (-) Length   343 a.a.
NCBI ID   WP_000506425.1    Uniprot ID   A0A9P1QFQ7
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   regulate competence (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1731482..1753716 1740363..1741394 within 0


Gene organization within MGE regions


Location: 1731482..1753716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS08735 - 1731518..1732747 (+) 1230 WP_279514573.1 ISL3 family transposase -
  ACE2AN_RS08740 groL 1732846..1734468 (-) 1623 WP_000031585.1 chaperonin GroEL -
  ACE2AN_RS08745 groES 1734484..1734768 (-) 285 WP_000917330.1 co-chaperone GroES -
  ACE2AN_RS08750 ssbB/cilA 1735038..1735433 (-) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  ACE2AN_RS08755 - 1735510..1736271 (-) 762 WP_001107755.1 SDR family NAD(P)-dependent oxidoreductase -
  ACE2AN_RS08760 ytpR 1736304..1736930 (-) 627 WP_000578309.1 YtpR family tRNA-binding protein -
  ACE2AN_RS08765 - 1736946..1737263 (-) 318 WP_000615767.1 thioredoxin family protein -
  ACE2AN_RS08770 - 1737260..1737559 (-) 300 WP_001013974.1 DUF4651 domain-containing protein -
  ACE2AN_RS08775 - 1737757..1737954 (-) 198 Protein_1715 N-acetylmuramoyl-L-alanine amidase family protein -
  ACE2AN_RS08780 - 1738196..1738870 (-) 675 WP_044813801.1 membrane protein -
  ACE2AN_RS08785 - 1738875..1739321 (-) 447 WP_044813800.1 LytTR family DNA-binding domain-containing protein -
  ACE2AN_RS08790 - 1739435..1739938 (-) 504 WP_000800923.1 phosphatase PAP2 family protein -
  ACE2AN_RS08795 - 1739935..1740297 (-) 363 WP_000078805.1 DUF2200 domain-containing protein -
  ACE2AN_RS08800 rcrQ 1740363..1741394 (-) 1032 WP_000506425.1 ABC transporter ATP-binding protein Regulator
  ACE2AN_RS08805 - 1741401..1742222 (-) 822 Protein_1721 ABC transporter permease -
  ACE2AN_RS08810 - 1742239..1742710 (-) 472 Protein_1722 MarR family winged helix-turn-helix transcriptional regulator -
  ACE2AN_RS08815 - 1742834..1743550 (-) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  ACE2AN_RS08820 ply 1744431..1745846 (-) 1416 WP_001284361.1 cholesterol-dependent cytolysin pneumolysin -
  ACE2AN_RS08825 - 1745857..1746267 (-) 411 WP_000595758.1 hypothetical protein -
  ACE2AN_RS08830 - 1746260..1746868 (-) 609 WP_000083614.1 hypothetical protein -
  ACE2AN_RS08835 - 1746881..1747339 (-) 459 WP_000186955.1 DUF4231 domain-containing protein -
  ACE2AN_RS08840 - 1747464..1747863 (+) 400 Protein_1728 transposase family protein -
  ACE2AN_RS08845 - 1748349..1749182 (+) 834 WP_050103383.1 glycerophosphodiester phosphodiesterase family protein -
  ACE2AN_RS08850 - 1749225..1750286 (+) 1062 WP_000475761.1 extracellular solute-binding protein -
  ACE2AN_RS08855 - 1750303..1751307 (+) 1005 WP_000627599.1 ABC transporter ATP-binding protein -
  ACE2AN_RS08860 - 1751319..1753013 (+) 1695 WP_001232286.1 iron ABC transporter permease -
  ACE2AN_RS08865 - 1753015..1753716 (+) 702 WP_001054457.1 MgtC/SapB family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37908.08 Da        Isoelectric Point: 4.4764

>NTDB_id=1052202 ACE2AN_RS08800 WP_000506425.1 1740363..1741394(-) (rcrQ) [Streptococcus pneumoniae strain 6_2F1]
MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDENFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTV
AFIGSTGSGKSTLVNLIPRFYDVSAGEILVDGVNVQDYDFSATAHAGQKVAIVGSTGTGKTTIVNLLMKFYEIDKGSIHI
DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHHFIMTLPDGYDTILDDTVTLSVG
QKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQKAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEE
LMAQGGFYADLYNSQFTEDEAEE

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1052202 ACE2AN_RS08800 WP_000506425.1 1740363..1741394(-) (rcrQ) [Streptococcus pneumoniae strain 6_2F1]
ATGGGCTTCCTTCTCATGGGAGCACTCTTCATCGTTCTTCCCCGAACTATGGTCTCTGCTAAGCGGATTAATCAAGTTTT
AGATTTGCATTCTTCTATCCAAAACCCTGTTCAAGTACAGCTGACTGATGAAAACTTCAAAGGTCAGGTCGAGTTTAAGG
ATGTGACCTTCCGCTATGCGGCAAATTCGGAGGCAGTTATTGAACATGTTAGCTTTAAAGCAGAAACTGGTCAAACAGTG
GCCTTTATTGGGTCAACAGGTTCTGGTAAATCAACTCTGGTCAATCTGATTCCACGTTTCTACGACGTGTCAGCAGGAGA
AATTCTGGTGGACGGTGTCAATGTTCAAGACTATGACTTCTCTGCGACAGCTCATGCTGGTCAAAAGGTTGCCATTGTTG
GGTCGACTGGGACTGGTAAGACAACCATTGTCAATCTTTTGATGAAATTCTATGAGATTGATAAGGGAAGTATTCACATT
GATGGTGTGGATACCAAGGCTATGACGCGTTCAGAAGTGCACGATGCCTTTTCAATGGTCTTGCAGGATACCTGGCTCTT
TGAAGGAACTATTCGAGACAATCTCATCTATAATCAAATAGGGATTAGTGATGAACGAATGATGGAAGCTAGTAAGGCTG
TGGGAATTCACCACTTTATTATGACCTTGCCAGATGGCTATGATACCATCTTGGATGACACCGTGACCTTGTCTGTAGGA
CAAAAACAACTATTGACTATTGCTCGTGCCCTTCTTAAGGATGCACCGCTTTTGATTTTGGATGAGGCGACTTCTTCTGT
TGACACACGGACAGAGGAATTGATCCAAAAAGCCATGGACCGTTTGATGGAAGGACGCACATCCTTTGTCATTGCCCACC
GCTTGTCAACCATCCGAAATGCAGACTTGATCTTGGTCATGAAAGATGGAAATATCATCGAGCAAGGCAACTATGAGGAA
CTGATGGCGCAAGGTGGCTTCTACGCTGACTTGTACAATAGTCAATTTACAGAAGATGAAGCAGAAGAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(120-265)

ABC transporter (ABC_tran)

(68-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rcrQ Streptococcus mutans UA159

80.357

65.306

0.525
  rcrP Streptococcus mutans UA159

37.861

100

0.382

Multiple sequence alignment