Detailed information NTG1007277

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: ABLU27_RS02870
• Genome accession: NZ_CP157500
• Coordinates: 473099..473482 (-)
• Length: 127 a.a.
• NCBI ID: WP_010906318.1
• Uniprot ID: A0A3N6KXZ7
• Organism: Lactococcus lactis strain 2B-9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 468099..478482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABLU27_RS02830 (ABLU27_02830)	-	468635..469444 (-)	810	WP_014570791.1	metal ABC transporter permease	-
ABLU27_RS02835 (ABLU27_02835)	-	469437..470174 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
ABLU27_RS02840 (ABLU27_02840)	-	470351..471193 (-)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
ABLU27_RS02845 (ABLU27_02845)	-	471190..471627 (-)	438	WP_058213216.1	zinc-dependent MarR family transcriptional regulator	-
ABLU27_RS02850 (ABLU27_02850)	comGG	471708..471992 (-)	285	WP_406834849.1	competence type IV pilus minor pilin ComGG	Machinery gene
ABLU27_RS02855 (ABLU27_02855)	comGF	472031..472477 (-)	447	WP_029344525.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABLU27_RS02860 (ABLU27_02860)	comGE	472440..472736 (-)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
ABLU27_RS02865 (ABLU27_02865)	comGD	472708..473106 (-)	399	WP_021214886.1	competence type IV pilus minor pilin ComGD	Machinery gene
ABLU27_RS02870 (ABLU27_02870)	comGC	473099..473482 (-)	384	WP_010906318.1	competence type IV pilus major pilin ComGC	Machinery gene
ABLU27_RS02875 (ABLU27_02875)	comGB	473496..474569 (-)	1074	WP_406835453.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABLU27_RS02880 (ABLU27_02880)	comGA	474463..475401 (-)	939	WP_058212859.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 127 a.a.
• Molecular weight: 14797.39 Da
• Isoelectric Point: 8.4538

>NTDB_id=1007277 ABLU27_RS02870 WP_010906318.1 473099..473482(-) (comGC) [Lactococcus lactis strain 2B-9]
MERTKKFILKKIQKIFLFVKICEKKCRQKELKAFTLIEMLIVLAIISILILLFVPNLIKEKSQVQKTGEAAVVKVVESQA
QLYELDHDDEKPSLSELLSAGMITQKQISAYDNYYDQNKNEERNFND

Nucleotide

• Length: 384 bp

>NTDB_id=1007277 ABLU27_RS02870 WP_010906318.1 473099..473482(-) (comGC) [Lactococcus lactis strain 2B-9]
ATGGAAAGAACAAAGAAGTTTATTTTAAAAAAAATACAAAAAATATTTTTATTCGTTAAAATTTGTGAAAAAAAATGCCG
TCAGAAAGAGCTAAAAGCTTTTACTTTGATAGAGATGTTAATTGTACTAGCTATTATTAGTATTTTGATATTACTATTTG
TTCCAAATTTAATTAAAGAAAAATCACAAGTTCAAAAAACTGGAGAAGCGGCAGTTGTCAAAGTAGTAGAAAGTCAAGCT
CAACTTTATGAATTAGATCATGATGATGAGAAGCCGAGTCTGTCAGAATTGCTCAGTGCAGGGATGATTACTCAAAAACA
AATTTCTGCTTACGATAATTACTATGATCAGAATAAAAATGAAGAACGAAATTTTAATGACTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (32-52)

3D structure

• AlphaFold DB: A0A3N6KXZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Lactococcus lactis subsp. cremoris KW2	81.034	91.339	0.74
comGC/cglC	Streptococcus mitis SK321	56.436	79.528	0.449
comYC	Streptococcus mutans UA159	55.446	79.528	0.441
comYC	Streptococcus mutans UA140	55.446	79.528	0.441
comYC	Streptococcus gordonii str. Challis substr. CH1	56.566	77.953	0.441
comGC/cglC	Streptococcus pneumoniae TIGR4	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae Rx1	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae D39	54.455	79.528	0.433
comGC/cglC	Streptococcus pneumoniae R6	54.455	79.528	0.433
comGC/cglC	Streptococcus mitis NCTC 12261	58.427	70.079	0.409
comYC	Streptococcus suis isolate S10	56.818	69.291	0.394