Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01172  |
| T6SS type | Type i4b |
| Strain | Acinetobacter baumannii ATCC 17978 |
| Replicon (RefSeq) | chromosome (NZ_CP049363) |
| Location | 2307326..2326736 |
| Function | effector translocation |
| Comment | - |
| References | [1] Ruiz FM et al (2015) Crystal Structure of Hcp from Acinetobacter baumannii: A Component of the Type VI Secretion System. PLoS One. 10(6):e0129691. [PudMed:26079269] [2] Weber BS et al (2013) Genomic and Functional Analysis of the Type VI Secretion System in Acinetobacter. PLoS One. 8(1):e55142. [PudMed:23365692] [3] Eijkelkamp BA et al (2013) H-NS Plays a Role in Expression of Acinetobacter baumannii Virulence Features. Infect Immun. 81(7):2574-83. [PudMed:23649094] [4] Carruthers MD et al (2013) Acinetobacter baumannii Utilizes a Type VI Secretion System for Bacterial Competition. PLoS One. 8(3):e59388. [PudMed:23527179] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssG | TssH | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| G6543_RS11030 | 2302400..2303578 | - | 1179 | WP_000813815.1 | cyanate transporter | ||
| G6543_RS11035 | 2303578..2304060 | - | 483 | WP_000646729.1 | nucleoside deaminase | ||
| G6543_RS11040 | 2304076..2304723 | - | 648 | WP_085916981.1 | ankyrin repeat domain-containing protein | ||
| G6543_RS11045 | 2304896..2305747 | + | 852 | WP_000460184.1 | LysR family transcriptional regulator | ||
| G6543_RS11050 | 2305750..2306703 | - | 954 | WP_000972583.1 | M15 family metallopeptidase | ||
| G6543_RS11055 | 2306711..2307313 | - | 603 | WP_000046451.1 | hypothetical protein | ||
| T6CP014910 | TssL | G6543_RS11060 | 2307326..2308132 | - | 807 | WP_000083625.1 | type IVB secretion system protein IcmH/DotU |
| T6CP014911 | TssK | G6543_RS11065 (tssK) | 2308150..2309514 | - | 1365 | WP_000471445.1 | type VI secretion system baseplate subunit TssK |
| T6CP014912 | TssA | G6543_RS11070 (tssA) | 2309531..2310625 | - | 1095 | WP_000020713.1 | type VI secretion system protein TssA |
| T6CP014913 | TssH | G6543_RS11075 (tssH) | 2310649..2313330 | - | 2682 | WP_156190132.1 | type VI secretion system ATPase TssH |
| G6543_RS11080 | 2313550..2313813 | - | 264 | WP_000168112.1 | PAAR domain-containing protein | ||
| G6543_RS11085 | 2313830..2314597 | - | 768 | WP_083028564.1 | OmpA family protein | ||
| G6543_RS11090 (tagF) | 2314600..2315559 | - | 960 | WP_000557241.1 | type VI secretion system-associated protein TagF | ||
| T6CP014914 | TssM | G6543_RS11095 (tssM) | 2315597..2319421 | - | 3825 | WP_000556914.1 | type VI secretion system membrane subunit TssM |
| G6543_RS11100 | 2319452..2320864 | - | 1413 | WP_000591882.1 | hypothetical protein | ||
| T6CP014915 | TssG | G6543_RS11105 (tssG) | 2320861..2321859 | - | 999 | WP_001190395.1 | type VI secretion system baseplate subunit TssG |
| G6543_RS11110 (tssF) | 2321823..2323633 | - | 1811 | pseudogene | type VI secretion system baseplate subunit TssF | ||
| T6CP014916 | TssE | G6543_RS11115 (tssE) | 2323650..2324126 | - | 477 | WP_001047031.1 | type VI secretion system baseplate subunit TssE |
| T6CP014917 | TssD | G6543_RS11120 | 2324206..2324709 | - | 504 | WP_000653195.1 | type VI secretion system tube protein Hcp |
| T6CP014918 | TssC | G6543_RS11125 (tssC) | 2324759..2326240 | - | 1482 | WP_001066523.1 | type VI secretion system contractile sheath large subunit |
| T6CP014919 | TssB | G6543_RS11130 (tssB) | 2326233..2326736 | - | 504 | WP_156190133.1 | type VI secretion system contractile sheath small subunit |
| G6543_RS11135 | 2326753..2327445 | - | 693 | WP_000869709.1 | hypothetical protein | ||
| G6543_RS11140 | 2328534..2328935 | + | 402 | WP_000070792.1 | hypothetical protein | ||
| G6543_RS11145 | 2329031..2329975 | + | 945 | WP_000542525.1 | ABC transporter permease | ||
| G6543_RS11150 | 2329975..2330856 | + | 882 | WP_001000091.1 | ABC transporter ATP-binding protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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