Detailed information of component protein


Summary

Component ID T6CP014918
Component protein type TssC
T6SS ID (Type) T6SS01172 experimental (Type i4b)
Strain Acinetobacter baumannii ATCC 17978
Replicon chromosome
Sequence Protein sequence (494 a.a.); Nucleotide sequence (1482 bp)
Reference
[1] Ruiz FM, Santillana E, Spínola-Amilibia M, et al. Crystal Structure of Hcp from Acinetobacter baumannii: A Component of the Type VI Secretion System. PLoS One. 2015 Jun 16;10(6):e0129691. doi: 10.1371/journal.pone.0129691. eCollection 2015. PMID: 26079269
[2] Weber BS, Miyata ST, Iwashkiw JA, et al. Genomic and functional analysis of the type VI secretion system in Acinetobacter. PLoS One. 2013;8(1):e55142. doi: 10.1371/journal.pone.0055142. Epub 2013 Jan 24. PMID: 23365692
[3] Carruthers MD, Nicholson PA, Tracy EN, et al. Acinetobacter baumannii utilizes a type VI secretion system for bacterial competition. PLoS One. 2013;8(3):e59388. doi: 10.1371/journal.pone.0059388. Epub 2013 Mar 19. PMID: 23527179
[4] Eijkelkamp BA, Stroeher UH, Hassan KA, et al. H-NS plays a role in expression of Acinetobacter baumannii virulence features. Infect Immun. 2013 Jul;81(7):2574-83. doi: 10.1128/IAI.00065-13. Epub 2013 May 6. PMID: 23649094
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) G6543_RS11125
Coordinate (Strand) 2324759..2326240 (-)
NCBI ID WP_001066523.1
RefSeq NZ_CP049363
Uniprot ID A0A7U4BM90_ACIBA, A0A0J0ZXP1_ACIBA, A0A427R4M7_9GAMM, A0A427XA76_9GAMM, A0A7U4DCX0_ACIBC, V5VEF2_ACIBA, A0A7U4DG00_ACIB5, A0A654KYL1_ACIBM, A0A5K6CSG4_ACIB3, A0A385EV12_ACIBA
KEGG ID abw:BL01_13270, abz:ABZJ_01455, abk:LX00_06410, abau:IX87_03970
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
VipB PF05943.14 4.6e-137 66..368
VipB_2 PF18945.2 6e-45 378..488
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-493 MNNTQSAAMPLVENEEVNLLDSIVEQSRIARNEEEHSRAKSLIGELAKEVMAGTITVSENMTLSIDKRIAEIDALISKQLSQIMHNEQFQKIESTWRGLYYFCQETPSNPLIKIRMLNTTKKELVKDFQGATDFDQSTLFKKIYEEEYGSFGGAPYSALIGDFEFDRTPSDMYLLEQISHVAAAAHAPFISAASPSILGLESFTDIDRPRDVSKIFETAEYVQWRSFRDSEDSRYVALTLPHVLGRLPYHPKEGTATEGFNFIEDVSGENHNEYLWMNAAYAFGTRLTNAFDMHGWCAAIRGVEGGGLVEGLPVHTFKTQDGEVVFKCPTEIAITDRREKELSDLGFIPLVHCKNTDYAAFFGAQSTQKPKKYDNDTANANSALSSQIQYIMAVSRIAHYLKAMMRDKVGSFASAGNVEAFLNEWLSQYVLLDDGASQEAKAQYPLREASVKVVEDPAQPGHYKSVVFLRPHFQLDELSVSLRLVTELPQSSN


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9838 - -


  Protein sequence: 494 a.a.    

>T6CP014918 NZ_CP049363:c2326240-2324759 [Acinetobacter baumannii] [TssC]
MNNTQSAAMPLVENEEVNLLDSIVEQSRIARNEEEHSRAKSLIGELAKEVMAGTITVSENMTLSIDKRIAEIDALISKQL
SQIMHNEQFQKIESTWRGLYYFCQETPSNPLIKIRMLNTTKKELVKDFQGATDFDQSTLFKKIYEEEYGSFGGAPYSALI
GDFEFDRTPSDMYLLEQISHVAAAAHAPFISAASPSILGLESFTDIDRPRDVSKIFETAEYVQWRSFRDSEDSRYVALTL
PHVLGRLPYHPKEGTATEGFNFIEDVSGENHNEYLWMNAAYAFGTRLTNAFDMHGWCAAIRGVEGGGLVEGLPVHTFKTQ
DGEVVFKCPTEIAITDRREKELSDLGFIPLVHCKNTDYAAFFGAQSTQKPKKYDNDTANANSALSSQIQYIMAVSRIAHY
LKAMMRDKVGSFASAGNVEAFLNEWLSQYVLLDDGASQEAKAQYPLREASVKVVEDPAQPGHYKSVVFLRPHFQLDELSV
SLRLVTELPQSSN*

  Nucleotide sequence: 1482 bp    

>T6CP014918 NZ_CP049363:c2326240-2324759 [Acinetobacter baumannii] [TssC]
ATGAATAATACTCAATCAGCAGCAATGCCACTTGTTGAAAATGAAGAAGTTAATCTTTTAGATTCGATTGTTGAACAAAG
CCGTATTGCACGAAATGAAGAAGAACATTCTCGTGCTAAAAGCTTAATTGGTGAGCTTGCTAAAGAAGTAATGGCAGGGA
CCATTACTGTTTCTGAAAATATGACTTTATCAATTGATAAGCGTATTGCAGAAATTGATGCTCTGATTTCAAAGCAGTTA
AGTCAGATCATGCACAATGAACAATTCCAAAAAATTGAGTCAACTTGGCGTGGTCTTTATTACTTTTGTCAGGAAACGCC
TTCAAATCCGCTCATTAAAATTCGTATGCTTAATACGACTAAGAAAGAGTTGGTAAAAGATTTCCAAGGTGCTACAGACT
TTGATCAAAGCACTTTGTTTAAGAAAATCTACGAAGAAGAATACGGTTCTTTTGGTGGTGCACCATACTCAGCATTAATT
GGTGATTTTGAGTTTGATCGTACTCCATCTGATATGTATTTGCTTGAGCAAATCTCTCATGTTGCAGCGGCAGCACATGC
ACCATTTATTTCAGCTGCTAGTCCGAGCATTTTAGGCCTTGAATCATTTACAGATATTGATCGTCCTAGAGATGTTTCAA
AAATCTTTGAAACCGCTGAATATGTTCAATGGCGTTCGTTCCGTGATAGTGAAGACTCACGTTATGTTGCATTGACTTTG
CCTCATGTCTTGGGTCGTCTCCCATATCATCCAAAAGAAGGTACTGCGACAGAAGGCTTTAATTTTATTGAAGATGTTTC
TGGTGAAAACCACAATGAATATTTGTGGATGAATGCAGCTTATGCTTTTGGTACTCGCTTAACAAATGCATTTGATATGC
ATGGTTGGTGTGCTGCTATTCGCGGTGTTGAAGGTGGTGGTTTAGTTGAAGGCTTGCCAGTACATACTTTTAAAACACAA
GATGGCGAAGTGGTATTCAAGTGTCCAACTGAAATTGCAATCACGGATCGCCGTGAAAAAGAGTTAAGCGATCTAGGCTT
CATTCCGTTAGTACATTGTAAAAATACAGATTACGCAGCTTTCTTTGGCGCGCAATCAACTCAAAAACCTAAAAAATATG
ACAATGATACAGCCAATGCAAACTCGGCTTTATCAAGTCAGATTCAGTACATCATGGCTGTTTCACGTATTGCACATTAC
TTAAAAGCAATGATGCGAGATAAAGTGGGTAGCTTTGCTTCTGCTGGAAATGTTGAAGCATTCTTAAATGAGTGGTTGTC
ACAGTATGTCTTACTTGACGATGGTGCTTCTCAAGAAGCAAAAGCTCAATACCCGTTACGTGAAGCGTCTGTAAAAGTTG
TAGAAGATCCTGCTCAACCAGGTCACTACAAATCTGTGGTTTTCTTGCGACCACATTTCCAGCTGGATGAGTTGTCGGTT
TCTTTACGACTTGTCACTGAGTTACCTCAGTCCTCAAATTAA