Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00111  |
| T6SS type | Type i3 |
| Strain | Burkholderia thailandensis E264 |
| Replicon (RefSeq) | chromosome II (NC_007650) |
| Location | 137720..169613 |
| Function | - |
| Comment | - |
| References | [1] Russell AB et al (2012) A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 11(5):538-49. [PudMed:22607806] [2] Schwarz S et al (2010) Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog. 6(8):e1001068. [PudMed:20865170] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagJ | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BTH_RS00590 | 132907..133461 | + | 555 | WP_011400800.1 | type 1 fimbrial protein | ||
| BTH_RS00595 | 133543..134268 | + | 726 | WP_011400801.1 | fimbria/pilus periplasmic chaperone | ||
| BTH_RS34170 | 134317..134475 | - | 159 | WP_162465482.1 | hypothetical protein | ||
| BTH_RS00600 | 134428..137124 | + | 2697 | WP_009894721.1 | fimbrial biogenesis outer membrane usher protein | ||
| BTH_RS00605 | 137117..137689 | + | 573 | WP_025988574.1 | type 1 fimbrial protein | ||
| T6CP009345 | TssL | BTH_RS00610 | 137720..138409 | + | 690 | WP_009907089.1 | DotU family type IV/VI secretion system protein |
| T6CP011369 | TagL | BTH_RS00615 | 138412..140088 | + | 1677 | WP_009894727.1 | OmpA family protein |
| T6CP001036 | TssB | BTH_RS00620 (tssB) | 140432..140971 | + | 540 | WP_009894728.1 | type VI secretion system contractile sheath small subunit |
| T6CP001037 | TssC | BTH_RS00625 (tssC) | 141005..142504 | + | 1500 | WP_009894729.1 | type VI secretion system contractile sheath large subunit |
| T6CP001038 | TssD | BTH_RS00630 | 142705..143187 | + | 483 | WP_009894730.1 | type VI secretion system tube protein Hcp |
| T6CP001039 | TssJ | BTH_RS00635 (tssJ) | 143315..143857 | + | 543 | WP_011400803.1 | type VI secretion system lipoprotein TssJ |
| T6CP001040 | TssK | BTH_RS00640 (tssK) | 143863..145212 | + | 1350 | WP_009894732.1 | type VI secretion system baseplate subunit TssK |
| T6CP001041 | TssL | BTH_RS00645 (tssL) | 145209..146510 | + | 1302 | WP_009894733.1 | type VI secretion system protein TssL, long form |
| T6CP001042 | TssM | BTH_RS00650 (tssM) | 146525..150433 | + | 3909 | WP_009894736.1 | type VI secretion system membrane subunit TssM |
| BTH_RS00655 | 150603..151172 | + | 570 | WP_009894738.1 | hypothetical protein | ||
| T6CP001043 | TssI | BTH_RS00660 (tssI) | 151273..153891 | + | 2619 | WP_011400805.1 | type VI secretion system tip protein VgrG |
| T6CP011370 | PAAR | BTH_RS00665 | 153966..154235 | + | 270 | WP_004523693.1 | PAAR domain-containing protein |
| BTH_RS00670 | 154248..157700 | + | 3453 | WP_011400806.1 | RHS repeat protein | ||
| BTH_RS00675 | 157593..158951 | - | 1359 | WP_038707671.1 | hypothetical protein | ||
| BTH_RS00680 | 158984..160012 | - | 1029 | WP_009894750.1 | fimbrial protein | ||
| T6CP001044 | TssA | BTH_RS00685 | 160068..161138 | - | 1071 | WP_009894751.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP001045 | TssG | BTH_RS00690 (tssG) | 161157..162206 | - | 1050 | WP_009894753.1 | type VI secretion system baseplate subunit TssG |
| T6CP001046 | TssF | BTH_RS00695 (tssF) | 162203..164083 | - | 1881 | WP_009894755.1 | type VI secretion system baseplate subunit TssF |
| T6CP001047 | TssE | BTH_RS00700 (tssE) | 164085..164603 | - | 519 | WP_009894757.1 | type VI secretion system baseplate subunit TssE |
| T6CP012722 | TagJ | BTH_RS00705 | 164590..165396 | - | 807 | WP_009894758.1 | ImpE protein |
| BTH_RS00710 | 165428..166411 | - | 984 | WP_171462744.1 | TagK domain-containing protein | ||
| T6CP001048 | TssH | BTH_RS00715 (tssH) | 166968..169613 | + | 2646 | WP_009907099.1 | type VI secretion system ATPase TssH |
| BTH_RS00720 | 170006..173047 | - | 3042 | WP_025370063.1 | response regulator | ||
| BTH_RS29330 | 173846..174040 | - | 195 | WP_009907100.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|