Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   EQB41_RS00115 Genome accession   NZ_LR129840
Coordinates   22169..22405 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17169..27405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS00105 - 20226..21072 (+) 847 Protein_14 IS630 family transposase -
  EQB41_RS00110 - 21107..21904 (-) 798 Protein_15 transposase -
  EQB41_RS00115 comW 22169..22405 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  EQB41_RS00120 - 22636..23922 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  EQB41_RS00125 - 24164..25312 (-) 1149 WP_000876726.1 tyrosine-type recombinase/integrase -
  EQB41_RS00130 - 25486..26298 (-) 813 WP_001174227.1 HIRAN domain-containing protein -
  EQB41_RS00135 - 26336..26716 (-) 381 Protein_20 ImmA/IrrE family metallo-endopeptidase -
  EQB41_RS00140 - 26729..26992 (-) 264 WP_000285962.1 type II toxin-antitoxin system RelE family toxin -
  EQB41_RS00145 - 26992..27225 (-) 234 WP_000156422.1 hypothetical protein -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=993612 EQB41_RS00115 WP_000939546.1 22169..22405(+) (comW) [Streptococcus pneumoniae strain 4496 isolate 4496]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=993612 EQB41_RS00115 WP_000939546.1 22169..22405(+) (comW) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987
  comW Streptococcus pneumoniae D39

98.718

100

0.987
  comW Streptococcus pneumoniae R6

98.718

100

0.987
  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756

Multiple sequence alignment