Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SP4011_RS01795 Genome accession   NZ_AP026968
Coordinates   328074..329330 (+) Length   418 a.a.
NCBI ID   WP_112445114.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 324036..336529 328074..329330 within 0


Gene organization within MGE regions


Location: 324036..336529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS01770 (SP4011_03110) - 324036..324899 (+) 864 WP_338619590.1 helix-turn-helix transcriptional regulator -
  SP4011_RS01775 (SP4011_03120) comM 325205..325825 (+) 621 WP_338619592.1 hypothetical protein Regulator
  SP4011_RS01780 (SP4011_03130) tsaE 326015..326458 (+) 444 WP_338619594.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SP4011_RS01785 (SP4011_03140) - 326448..326966 (+) 519 WP_061425432.1 GNAT family N-acetyltransferase -
  SP4011_RS01790 (SP4011_03150) brpA 326974..327990 (+) 1017 WP_338619597.1 biofilm formation/cell division transcriptional regulator BrpA -
  SP4011_RS01795 (SP4011_03160) cinA 328074..329330 (+) 1257 WP_112445114.1 competence/damage-inducible protein A Machinery gene
  SP4011_RS01800 (SP4011_03170) recA 329385..330551 (+) 1167 WP_050234077.1 recombinase RecA Machinery gene
  SP4011_RS01805 (SP4011_03180) - 330666..332036 (+) 1371 WP_338619599.1 MATE family efflux transporter -
  SP4011_RS01810 (SP4011_03190) - 332412..333362 (+) 951 WP_338619601.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SP4011_RS01815 (SP4011_03200) - 333733..334077 (+) 345 WP_261144334.1 helix-turn-helix domain-containing protein -
  SP4011_RS01820 (SP4011_03210) - 334090..334836 (+) 747 WP_338620384.1 ImmA/IrrE family metallo-endopeptidase -
  SP4011_RS01825 (SP4011_03220) - 334829..335251 (+) 423 Protein_327 hypothetical protein -
  SP4011_RS01830 (SP4011_03230) - 336026..336529 (+) 504 WP_175880460.1 PBECR4 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45188.45 Da        Isoelectric Point: 4.5056

>NTDB_id=99092 SP4011_RS01795 WP_112445114.1 328074..329330(+) (cinA) [Streptococcus parapneumoniae strain SP4011]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDPQAQEKLDVFFAQRPDYARTPNNERQAQIVEGATPLPNETGLAVGGILEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKASNQEEANQVLDILEHQI
LNRQTFEGLSLRELCYGYGEETSLASIVVEELKKQEKTITAAESLTAGLFQATVADFSGASSIFKGGFVTYSLEEKSKML
DIPVKDLEEHGVVSEFTAQKMAEQARSKTQSDFGLSLTGVAGPDSLEGQPAGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=99092 SP4011_RS01795 WP_112445114.1 328074..329330(+) (cinA) [Streptococcus parapneumoniae strain SP4011]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAAATTGTCAACACCAATGCCCAGTTTTTATCAGA
AAAACTAGCAGAGATTGGAGTGGACGTATATTTTCAGACGGCTGTAGGAGACAACGAAGCCCGTCTCTTATCCTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGTGGTTTAGGGCCAACTGAGGACGATTTGACCAAACAAACT
CTGGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATCCTCAGGCCCAGGAGAAGTTGGATGTCTTTTTTGCCCAGAGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGACTCCACTGCCAAACGAAACAGGAC
TGGCTGTGGGAGGAATATTGGAAGTCGATGGAGTGACATACGTCGTCCTTCCAGGTCCACCAAGTGAATTGAAACCCATG
GTTTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTATATTCCCGAGTTCTTCGTTTCTTTGGAATTGGCGA
AAGCCAGCTGGTGACCATTTTGGCTGATTTGATTGATAATCAAACAGATCCGACCTTGGCACCTTATGCCAAGACAGGAG
AAGTAACTCTACGTCTGTCAACAAAAGCTAGCAATCAAGAAGAGGCGAATCAAGTGCTGGATATTTTGGAACATCAAATC
TTGAATCGCCAAACTTTTGAAGGCCTTTCTTTACGAGAACTTTGTTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAAACAAGAGAAAACCATCACGGCTGCCGAGAGTTTGACGGCAGGTCTTTTCCAAGCGACCG
TGGCTGATTTTTCGGGCGCTTCCAGTATATTTAAGGGTGGTTTTGTGACCTATAGCCTGGAGGAAAAATCAAAGATGTTG
GATATTCCTGTCAAGGATTTGGAAGAGCACGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCGCGAAG
CAAGACCCAGTCTGATTTTGGCCTTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGGCAGCCAGCTGGGACAG
TCTTCATAGGCTTGGCTCAAGAGCAAGGAACTGAGGTTATCAAGGTGAATATTGGAGGCAGAAGTCGAGCAGATGTACGA
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

97.129

100

0.971
  cinA Streptococcus mitis NCTC 12261

96.411

100

0.964
  cinA Streptococcus pneumoniae TIGR4

93.301

100

0.933
  cinA Streptococcus pneumoniae Rx1

93.062

100

0.931
  cinA Streptococcus pneumoniae R6

93.062

100

0.931
  cinA Streptococcus pneumoniae D39

92.823

100

0.928
  cinA Streptococcus mutans UA159

72.249

100

0.722
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment