Detailed information NTG0099091

Bioinformatically predicted

Overview

• Name: comM
• Type: Regulator
• Locus tag: SP4011_RS01775
• Genome accession: NZ_AP026968
• Coordinates: 325205..325825 (+)
• Length: 206 a.a.
• NCBI ID: WP_338619592.1
• Uniprot ID: -
• Organism: Streptococcus parapneumoniae strain SP4011
• Function: fratricide immunity (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	324036..336529	325205..325825	within	0

Gene organization within MGE regions

Location: 324036..336529

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP4011_RS01770 (SP4011_03110)	-	324036..324899 (+)	864	WP_338619590.1	helix-turn-helix transcriptional regulator	-
SP4011_RS01775 (SP4011_03120)	comM	325205..325825 (+)	621	WP_338619592.1	hypothetical protein	Regulator
SP4011_RS01780 (SP4011_03130)	tsaE	326015..326458 (+)	444	WP_338619594.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
SP4011_RS01785 (SP4011_03140)	-	326448..326966 (+)	519	WP_061425432.1	GNAT family N-acetyltransferase	-
SP4011_RS01790 (SP4011_03150)	brpA	326974..327990 (+)	1017	WP_338619597.1	biofilm formation/cell division transcriptional regulator BrpA	-
SP4011_RS01795 (SP4011_03160)	cinA	328074..329330 (+)	1257	WP_112445114.1	competence/damage-inducible protein A	Machinery gene
SP4011_RS01800 (SP4011_03170)	recA	329385..330551 (+)	1167	WP_050234077.1	recombinase RecA	Machinery gene
SP4011_RS01805 (SP4011_03180)	-	330666..332036 (+)	1371	WP_338619599.1	MATE family efflux transporter	-
SP4011_RS01810 (SP4011_03190)	-	332412..333362 (+)	951	WP_338619601.1	N-acetylmuramoyl-L-alanine amidase family protein	-
SP4011_RS01815 (SP4011_03200)	-	333733..334077 (+)	345	WP_261144334.1	helix-turn-helix domain-containing protein	-
SP4011_RS01820 (SP4011_03210)	-	334090..334836 (+)	747	WP_338620384.1	ImmA/IrrE family metallo-endopeptidase	-
SP4011_RS01825 (SP4011_03220)	-	334829..335251 (+)	423	Protein_327	hypothetical protein	-
SP4011_RS01830 (SP4011_03230)	-	336026..336529 (+)	504	WP_175880460.1	PBECR4 domain-containing protein	-

Sequence

Protein

• Length: 206 a.a.
• Molecular weight: 23550.76 Da
• Isoelectric Point: 10.1254

>NTDB_id=99091 SP4011_RS01775 WP_338619592.1 325205..325825(+) (comM) [Streptococcus parapneumoniae strain SP4011]
MKSMRILFLLVLIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYMRDLLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIATLIFF

Nucleotide

• Length: 621 bp

>NTDB_id=99091 SP4011_RS01775 WP_338619592.1 325205..325825(+) (comM) [Streptococcus parapneumoniae strain SP4011]
ATGAAATCAATGAGAATCTTATTTTTGTTAGTCTTAATTCAAATTAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTTATCGGAAGTATGGTCTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTCTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTTTTCTTTCTATTTGGGCTAGATTTGTTGATTTTTTTACCCTTAAAAAAATACATGCGCGATTTGC
TTGCTATGCTAGATAGAAAAAAGACGGTGTTGGTGACTATTTTAGCAACACTTCTCTTCTTAAGAAATCCAATGACCATT
GTCTCTCTTCTGATTTATATTGGACTGGGTTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAAAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGCTACACTCATTTTCTTTTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comM	Streptococcus pneumoniae D39	98.058	100	0.981
comM	Streptococcus pneumoniae R6	98.058	100	0.981
comM	Streptococcus pneumoniae TIGR4	98.058	100	0.981
comM	Streptococcus mitis SK321	38.974	94.66	0.369
comM	Streptococcus mitis NCTC 12261	38.462	94.66	0.364