Detailed information NTG0989186

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: AAFQ93_RS08350
• Genome accession: NZ_CP152419
• Coordinates: 1748592..1749332 (-)
• Length: 246 a.a.
• NCBI ID: WP_223139926.1
• Uniprot ID: -
• Organism: Streptococcus nidrosiense strain SO-23-1
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1743592..1754332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAFQ93_RS08330 (AAFQ93_08270)	-	1744202..1744519 (-)	318	WP_375555168.1	hypothetical protein	-
AAFQ93_RS08335 (AAFQ93_08275)	-	1745834..1746061 (-)	228	WP_375555169.1	Blp family class II bacteriocin	-
AAFQ93_RS08340 (AAFQ93_08280)	-	1746252..1746548 (-)	297	WP_049509274.1	bacteriocin immunity protein	-
AAFQ93_RS08345 (AAFQ93_08285)	-	1747256..1748581 (-)	1326	WP_375555170.1	GHKL domain-containing protein	-
AAFQ93_RS08350 (AAFQ93_08290)	comE/blpR	1748592..1749332 (-)	741	WP_223139926.1	response regulator transcription factor	Regulator
AAFQ93_RS08355 (AAFQ93_08295)	-	1749343..1749675 (-)	333	WP_223139927.1	LytTR family DNA-binding domain-containing protein	-
AAFQ93_RS08360 (AAFQ93_08300)	-	1750143..1751477 (-)	1335	WP_004260041.1	Nramp family divalent metal transporter	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28903.25 Da
• Isoelectric Point: 6.6123

>NTDB_id=989186 AAFQ93_RS08350 WP_223139926.1 1748592..1749332(-) (comE/blpR) [Streptococcus nidrosiense strain SO-23-1]
MNIFILEDNFLQQTRIENIVKKILVDNKVEYRHFEVYGKPQQLLEDISERGNHQLFLLDIEIKDDDKRGLDVAREIRKLD
SQAVIAFVTSHSEFMPVSFEYLVSAIDFIDKELPEPLFIKRIENVISSVRDNQRRTVSEDSFIFTGSKAQIQVPFKDLLY
IETSTIAHKLTLYSKRDIVEFYGQLSDILKQEPRLFQCHRSFIVNPYNISLIDKENRLVHFQNGSSCIVSRLKIRPLMKA
IERLHD

Nucleotide

• Length: 741 bp

>NTDB_id=989186 AAFQ93_RS08350 WP_223139926.1 1748592..1749332(-) (comE/blpR) [Streptococcus nidrosiense strain SO-23-1]
GTGAATATTTTTATACTAGAAGATAATTTTTTACAACAGACTAGAATTGAAAATATTGTCAAAAAAATTTTGGTGGATAA
TAAGGTTGAGTATAGGCATTTTGAGGTTTATGGAAAACCTCAACAGCTTTTAGAGGACATTTCAGAGAGAGGAAATCATC
AATTATTTTTACTTGATATTGAAATAAAAGATGATGACAAAAGAGGATTAGACGTTGCTAGAGAAATTAGAAAACTTGAT
TCTCAAGCAGTGATTGCTTTTGTAACATCACATTCTGAGTTTATGCCTGTATCTTTTGAATATTTAGTATCAGCTATTGA
TTTCATTGATAAAGAATTACCTGAACCATTATTTATCAAACGAATTGAAAATGTTATTTCAAGTGTTAGAGATAATCAAA
GAAGAACAGTATCTGAGGACTCTTTTATATTTACAGGATCCAAAGCTCAAATTCAAGTCCCTTTTAAAGATTTATTGTAT
ATTGAAACATCAACAATTGCTCATAAGTTGACTCTCTATTCCAAACGAGACATAGTTGAATTTTATGGACAATTGTCAGA
TATTCTTAAACAGGAACCACGTTTATTTCAATGTCATAGATCATTTATCGTAAATCCTTATAATATATCTTTAATTGATA
AAGAAAATCGATTAGTTCATTTTCAGAACGGGTCCTCTTGTATTGTCTCTAGATTAAAAATTCGTCCACTTATGAAAGCT
ATCGAAAGACTTCATGACTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	51.653	98.374	0.508
comE/comE1	Streptococcus equinus JB1	44.538	96.748	0.431
comE	Streptococcus mitis SK321	36.8	100	0.374
comE	Streptococcus mitis NCTC 12261	36.8	100	0.374
comE	Streptococcus pneumoniae Rx1	36.4	100	0.37
comE	Streptococcus pneumoniae D39	36.4	100	0.37
comE	Streptococcus pneumoniae R6	36.4	100	0.37
comE	Streptococcus pneumoniae TIGR4	36.4	100	0.37
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.759	97.967	0.37
comE/comE2	Streptococcus gordonii strain NCTC7865	37.759	97.967	0.37
comE	Streptococcus infantis strain Atu-4	35.6	100	0.362
comE/comE2	Streptococcus equinus JB1	36.475	99.187	0.362