Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8570_RS02345 Genome accession   NZ_AP026932
Coordinates   473492..475168 (-) Length   558 a.a.
NCBI ID   WP_196300924.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 468492..480168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS02315 (PC1528_04610) - 468823..469152 (-) 330 WP_000132572.1 hypothetical protein -
  R8570_RS02320 (PC1528_04620) - 469429..469767 (+) 339 WP_000682132.1 LytTR family DNA-binding domain-containing protein -
  R8570_RS02325 (PC1528_04630) comE/blpR 469772..470509 (+) 738 WP_001219146.1 response regulator transcription factor Regulator
  R8570_RS02330 (PC1528_04640) - 470523..471863 (+) 1341 WP_001099895.1 sensor histidine kinase -
  R8570_RS02335 (PC1528_04650) blpC 471908..472063 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  R8570_RS02340 (PC1528_04660) - 472120..473481 (-) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  R8570_RS02345 (PC1528_04670) comA/nlmT 473492..475168 (-) 1677 WP_196300924.1 peptide cleavage/export ABC transporter Regulator
  R8570_RS02350 (PC1528_04680) comA/nlmT 475062..475649 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8570_RS02355 (PC1528_04690) blpU 475930..476160 (+) 231 WP_001093268.1 bacteriocin-like peptide BlpU -
  R8570_RS02360 - 476163..476282 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  R8570_RS02365 (PC1528_04700) - 476579..476743 (+) 165 WP_000727118.1 hypothetical protein -
  R8570_RS02370 (PC1528_04710) - 476740..477144 (+) 405 WP_000846944.1 hypothetical protein -
  R8570_RS02375 - 477342..478147 (+) 806 Protein_466 IS5 family transposase -
  R8570_RS02380 (PC1528_04740) blpM 478349..478603 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  R8570_RS02385 (PC1528_04750) blpN 478619..478822 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  R8570_RS02390 (PC1528_04760) cipB 479066..479215 (+) 150 WP_001813641.1 bacteriocin-like peptide BlpO Regulator
  R8570_RS02395 - 479319..479438 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62949.24 Da        Isoelectric Point: 6.7844

>NTDB_id=98880 R8570_RS02345 WP_196300924.1 473492..475168(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701549]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=98880 R8570_RS02345 WP_196300924.1 473492..475168(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701549]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGACATATTTCTATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.07

99.821

0.729
  comA Streptococcus mitis NCTC 12261

67.563

100

0.676
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus mitis SK321

67.025

100

0.67
  comA Streptococcus gordonii str. Challis substr. CH1

66.905

100

0.67
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668

Multiple sequence alignment