Detailed information NTG0098738

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: R8624_RS04275
• Genome accession: NZ_AP026930
• Coordinates: 836325..838565 (+)
• Length: 746 a.a.
• NCBI ID: WP_050210311.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701208
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 831325..843565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8624_RS04245 (PC1195_08280)	-	831488..832456 (+)	969	WP_000658183.1	PhoH family protein	-
R8624_RS04250 (PC1195_08290)	-	832636..833136 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
R8624_RS04255 (PC1195_08300)	-	833139..833465 (+)	327	Protein_838	TfoX/Sxy family protein	-
R8624_RS04260	ald	833766..834877 (-)	1112	Protein_839	alanine dehydrogenase	-
R8624_RS04265 (PC1195_08340)	-	835054..835623 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
R8624_RS04270 (PC1195_08350)	comEA/celA/cilE	835691..836341 (+)	651	WP_050210310.1	helix-hairpin-helix domain-containing protein	Machinery gene
R8624_RS04275 (PC1195_08360)	comEC/celB	836325..838565 (+)	2241	WP_050210311.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R8624_RS04280 (PC1195_08370)	-	838744..838932 (+)	189	WP_050210312.1	hypothetical protein	-
R8624_RS04285 (PC1195_08380)	-	838964..839551 (+)	588	WP_050210313.1	ATP-binding cassette domain-containing protein	-
R8624_RS04290 (PC1195_08390)	-	839555..840736 (+)	1182	WP_000655935.1	membrane protein	-
R8624_RS04295 (PC1195_08400)	infC	841043..841573 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
R8624_RS04300 (PC1195_08410)	rpmI	841606..841806 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
R8624_RS04305 (PC1195_08420)	rplT	841858..842217 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
R8624_RS04310 (PC1195_08430)	-	842275..842655 (+)	381	WP_050219036.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84606.14 Da
• Isoelectric Point: 9.2732

>NTDB_id=98738 R8624_RS04275 WP_050210311.1 836325..838565(+) (comEC/celB) [Streptococcus pneumoniae strain PZ900701208]
MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCLFFQFPWKSAGKVLVICGVFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLWDITGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKQYPYLEVDVLKAAQHGSKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=98738 R8624_RS04275 WP_050210311.1 836325..838565(+) (comEC/celB) [Streptococcus pneumoniae strain PZ900701208]
ATGTTACAGTGGATTAAGAACATCCCCATTCCCCTAATTTACCTGAGTTTTTTGTTACTTTGGTTTTATTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCATGGAAATCAGCAG
GCAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGCCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTCTGCCTGACACTGTTAAGGTCAATGGTGATAGTCTGTCCTTTCGCGGCAA
GGCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTTTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTAACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTATGGGATATAACTGGGAAAAC
CATTCTCATAGATGTCGGTGGCAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCAATATCCTTACTTAGA
GGTGGATGTATTGAAAGCTGCCCAACATGGCTCTAAAAAGTCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-697)

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (31-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae D39	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae R6	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae TIGR4	95.576	100	0.956
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC/celB	Streptococcus mitis NCTC 12261	91.409	99.866	0.913
comEC	Lactococcus lactis subsp. cremoris KW2	44.355	99.732	0.442