Detailed information NTG0098737

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: R8624_RS04270
• Genome accession: NZ_AP026930
• Coordinates: 835691..836341 (+)
• Length: 216 a.a.
• NCBI ID: WP_050210310.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701208
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 830691..841341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8624_RS04240 (PC1195_08270)	-	831187..831402 (+)	216	WP_001232081.1	YozE family protein	-
R8624_RS04245 (PC1195_08280)	-	831488..832456 (+)	969	WP_000658183.1	PhoH family protein	-
R8624_RS04250 (PC1195_08290)	-	832636..833136 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
R8624_RS04255 (PC1195_08300)	-	833139..833465 (+)	327	Protein_838	TfoX/Sxy family protein	-
R8624_RS04260	ald	833766..834877 (-)	1112	Protein_839	alanine dehydrogenase	-
R8624_RS04265 (PC1195_08340)	-	835054..835623 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
R8624_RS04270 (PC1195_08350)	comEA/celA/cilE	835691..836341 (+)	651	WP_050210310.1	helix-hairpin-helix domain-containing protein	Machinery gene
R8624_RS04275 (PC1195_08360)	comEC/celB	836325..838565 (+)	2241	WP_050210311.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R8624_RS04280 (PC1195_08370)	-	838744..838932 (+)	189	WP_050210312.1	hypothetical protein	-
R8624_RS04285 (PC1195_08380)	-	838964..839551 (+)	588	WP_050210313.1	ATP-binding cassette domain-containing protein	-
R8624_RS04290 (PC1195_08390)	-	839555..840736 (+)	1182	WP_000655935.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23251.61 Da
• Isoelectric Point: 5.5171

>NTDB_id=98737 R8624_RS04270 WP_050210310.1 835691..836341(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701208]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLLVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGTKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=98737 R8624_RS04270 WP_050210310.1 835691..836341(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701208]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCTTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAGCTTAAACAGGTTAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATAGACCATCGTGAGGCAAATGG
GAAATTCAAGTCGATTGATGAACTCAAGAAGGTCTCTGGCATTGGTACTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	97.222	100	0.972
comEA/celA/cilE	Streptococcus pneumoniae D39	97.222	100	0.972
comEA/celA/cilE	Streptococcus pneumoniae R6	97.222	100	0.972
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.37	100	0.954
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	44.053	100	0.463
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37
comEA	Bacillus subtilis subsp. subtilis str. 168	42.105	87.963	0.37