Detailed information NTG0098739

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8624_RS04390
• Genome accession: NZ_AP026930
• Coordinates: 857260..858213 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain PZ900701208
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 852260..863213

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8624_RS04365	rpmG	853003..853152 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R8624_RS04370 (PC1195_08540)	secG	853192..853425 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8624_RS04375 (PC1195_08550)	rnr	853527..855881 (+)	2355	WP_000654886.1	ribonuclease R	-
R8624_RS04380 (PC1195_08560)	smpB	855844..856311 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8624_RS04385 (PC1195_08570)	tehB	856327..857187 (+)	861	WP_317650328.1	SAM-dependent methyltransferase TehB	-
R8624_RS04390 (PC1195_08580)	coiA	857260..858213 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R8624_RS04395 (PC1195_08590)	pepF	858232..860043 (+)	1812	WP_050311660.1	oligoendopeptidase F	Regulator
R8624_RS04400 (PC1195_08600)	-	860045..860758 (+)	714	WP_000230399.1	O-methyltransferase	-
R8624_RS04405 (PC1195_08610)	prsA	860825..861766 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R8624_RS04410 (PC1195_08620)	-	861885..862226 (-)	342	Protein_869	transposase	-
R8624_RS04415	-	862638..862733 (+)	96	Protein_870	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=98739 R8624_RS04390 WP_000495909.1 857260..858213(+) (coiA) [Streptococcus pneumoniae strain PZ900701208]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=98739 R8624_RS04390 WP_000495909.1 857260..858213(+) (coiA) [Streptococcus pneumoniae strain PZ900701208]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435