Detailed information NTG0986309

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: NST80_RS02435
• Genome accession: NZ_CP152039
• Coordinates: 467544..468278 (+)
• Length: 244 a.a.
• NCBI ID: WP_002886762.1
• Uniprot ID: A0AB37CQW6
• Organism: Streptococcus sp. FSL K6-1323
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 462544..473278

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NST80_RS02420 (NST80_02420)	-	462958..465540 (+)	2583	WP_183138110.1	SH3 domain-containing protein	-
NST80_RS02425 (NST80_02425)	-	465743..466495 (+)	753	WP_183138111.1	response regulator transcription factor	-
NST80_RS02430 (NST80_02430)	-	466630..467295 (+)	666	WP_183138112.1	DUF6287 domain-containing protein	-
NST80_RS02435 (NST80_02435)	comE/blpR	467544..468278 (+)	735	WP_002886762.1	response regulator transcription factor	Regulator
NST80_RS02440 (NST80_02440)	-	468275..469594 (+)	1320	WP_183138113.1	GHKL domain-containing protein	-
NST80_RS02445 (NST80_02445)	-	469692..470258 (+)	567	WP_002886764.1	transcriptional regulator	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28602.00 Da
• Isoelectric Point: 6.3896

>NTDB_id=986309 NST80_RS02435 WP_002886762.1 467544..468278(+) (comE/blpR) [Streptococcus sp. FSL K6-1323]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLDFITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKS
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRLESIILLTCKKIQSQNPEDAFRIENVKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLVNPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=986309 NST80_RS02435 WP_002886762.1 467544..468278(+) (comE/blpR) [Streptococcus sp. FSL K6-1323]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTGGGCGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGACTTTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCCTAGACATTCAGATTAAAGACGATACTAAAAAAGGCTTGGAAGTTGCAAAGCAGATTCGCAAGAGT
GACCCCTATGCCAATATTGTTTTCTTCACGACTCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAATTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTCTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGTTAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACTTTGAGACCTCGGATATCGTCCACAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
TCAAATTGAAAAGAGTGACCCTAGACTGTTTAAATGTCATAAGTCCTTCCTAGTTAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACGGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTACTTGAG
AGAATTAGCCTATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-242)

• Response regulator receiver domain (Response_reg) (6-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.049	100	0.52
comE/comE1	Streptococcus equinus JB1	47.28	97.951	0.463
comE/comE2	Streptococcus equinus JB1	42.562	99.18	0.422
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.86	99.59	0.377
comE/comE2	Streptococcus gordonii strain NCTC7865	37.86	99.59	0.377
comE	Streptococcus infantis strain Atu-4	37.759	98.77	0.373
comE	Streptococcus pneumoniae R6	37.344	98.77	0.369
comE	Streptococcus pneumoniae TIGR4	37.344	98.77	0.369
comE	Streptococcus pneumoniae D39	37.344	98.77	0.369
comE	Streptococcus mitis NCTC 12261	37.344	98.77	0.369
comE	Streptococcus pneumoniae Rx1	37.344	98.77	0.369
comE	Streptococcus mitis SK321	37.344	98.77	0.369