Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGD/cglD   Type   Machinery gene
Locus tag   R8522_RS10445 Genome accession   NZ_AP026916
Coordinates   2020699..2021103 (-) Length   134 a.a.
NCBI ID   WP_000588007.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2015699..2026103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS10405 (PC0006_20790) rnpA 2016120..2016491 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8522_RS10410 - 2016508..2016639 (-) 132 WP_000768904.1 hypothetical protein -
  R8522_RS10415 (PC0006_20800) - 2016640..2017830 (-) 1191 WP_000167759.1 acetate kinase -
  R8522_RS10420 (PC0006_20810) comYH 2017881..2018834 (-) 954 WP_000345123.1 class I SAM-dependent methyltransferase Machinery gene
  R8522_RS10425 (PC0006_20820) - 2018895..2019482 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  R8522_RS10430 (PC0006_20830) comGG/cglG 2019619..2020032 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8522_RS10435 comGF/cglF 2020010..2020471 (-) 462 WP_000250548.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8522_RS10440 (PC0006_20850) comGE/cglE 2020434..2020736 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8522_RS10445 (PC0006_20860) comGD/cglD 2020699..2021103 (-) 405 WP_000588007.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8522_RS10450 (PC0006_20870) comGC/cglC 2021096..2021422 (-) 327 WP_000738624.1 competence type IV pilus major pilin ComGC Machinery gene
  R8522_RS10455 (PC0006_20880) comGB/cglB 2021424..2022440 (-) 1017 WP_078140087.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8522_RS10460 (PC0006_20890) comGA/cglA/cilD 2022388..2023329 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  R8522_RS10465 (PC0006_20900) - 2023405..2023770 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8522_RS10470 (PC0006_20910) - 2023921..2024979 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence


Protein


Download         Length: 134 a.a.        Molecular weight: 14668.85 Da        Isoelectric Point: 10.2164

>NTDB_id=97675 R8522_RS10445 WP_000588007.1 2020699..2021103(-) (comGD/cglD) [Streptococcus pneumoniae strain PZ900700006]
MIKAFTMLESLLVLGFVSILALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLPV
PKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN

Nucleotide


Download         Length: 405 bp        

>NTDB_id=97675 R8522_RS10445 WP_000588007.1 2020699..2021103(-) (comGD/cglD) [Streptococcus pneumoniae strain PZ900700006]
ATGATTAAGGCCTTTACCATGCTGGAAAGTCTCTTGGTTTTGGGTTTTGTGAGTATCCTTGCCTTGGGCTTGTCCGGCTC
TGTTCAGTCCACTTTTGCGGCGGTAGAGGAACAGATTTTCTTTATGGAGTTTGAAGAACTCTATCGGGAAACCCAAAAAC
GCAGTGTAGCCAGTCAGCAAAAGACTAGTCTGAACTTAGATGGGCAGACGCTTAGCAATGGCAGTCAAAAGTTGCCAGTC
CCTAAAGGAATTCAGGCCCCATCAGGTCAAAGTATTACATTTGACCGTGCTGGGGGCAATTCGTCCCTGGCTAAGGTTGA
ATTTCAGACCAGTAAAGGAGCGATTCGCTATCAATTATATCTAGGAAATGGAAAAATTAAACGCATTAAGGAAACAAAAA
ATTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus pneumoniae TIGR4

98.507

100

0.985

  comGD/cglD Streptococcus pneumoniae Rx1

96.269

100

0.963

  comGD/cglD Streptococcus pneumoniae D39

96.269

100

0.963

  comGD/cglD Streptococcus pneumoniae R6

96.269

100

0.963

  comGD/cglD Streptococcus mitis NCTC 12261

96.241

99.254

0.955

  comGD/cglD Streptococcus mitis SK321

95.522

100

0.955

  comYD Streptococcus gordonii str. Challis substr. CH1

59.055

94.776

0.56

  comYD Streptococcus mutans UA140

49.219

95.522

0.47

  comYD Streptococcus mutans UA159

49.219

95.522

0.47


Multiple sequence alignment