Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8522_RS10420 Genome accession   NZ_AP026916
Coordinates   2017881..2018834 (-) Length   317 a.a.
NCBI ID   WP_000345123.1    Uniprot ID   A0A0U0M6F6
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2012881..2023834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS10390 (PC0006_20760) - 2013642..2014265 (-) 624 WP_000932644.1 hypothetical protein -
  R8522_RS10395 (PC0006_20770) jag 2014316..2015302 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  R8522_RS10400 (PC0006_20780) - 2015321..2016145 (-) 825 WP_209022237.1 membrane protein insertase YidC -
  R8522_RS10405 (PC0006_20790) rnpA 2016120..2016491 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8522_RS10410 - 2016508..2016639 (-) 132 WP_000768904.1 hypothetical protein -
  R8522_RS10415 (PC0006_20800) - 2016640..2017830 (-) 1191 WP_000167759.1 acetate kinase -
  R8522_RS10420 (PC0006_20810) comYH 2017881..2018834 (-) 954 WP_000345123.1 class I SAM-dependent methyltransferase Machinery gene
  R8522_RS10425 (PC0006_20820) - 2018895..2019482 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  R8522_RS10430 (PC0006_20830) comGG/cglG 2019619..2020032 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8522_RS10435 comGF/cglF 2020010..2020471 (-) 462 WP_000250548.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8522_RS10440 (PC0006_20850) comGE/cglE 2020434..2020736 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8522_RS10445 (PC0006_20860) comGD/cglD 2020699..2021103 (-) 405 WP_000588007.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8522_RS10450 (PC0006_20870) comGC/cglC 2021096..2021422 (-) 327 WP_000738624.1 competence type IV pilus major pilin ComGC Machinery gene
  R8522_RS10455 (PC0006_20880) comGB/cglB 2021424..2022440 (-) 1017 WP_078140087.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8522_RS10460 (PC0006_20890) comGA/cglA/cilD 2022388..2023329 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  R8522_RS10465 (PC0006_20900) - 2023405..2023770 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35747.95 Da        Isoelectric Point: 4.2434

>NTDB_id=97671 R8522_RS10420 WP_000345123.1 2017881..2018834(-) (comYH) [Streptococcus pneumoniae strain PZ900700006]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMVDVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=97671 R8522_RS10420 WP_000345123.1 2017881..2018834(-) (comYH) [Streptococcus pneumoniae strain PZ900700006]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGTAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U0M6F6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment