Detailed information NTG0972977

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: AAAF57_RS07915
• Genome accession: NZ_CP150847
• Coordinates: 1729954..1730688 (-)
• Length: 244 a.a.
• NCBI ID: WP_155213913.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS5
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1724954..1735688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAAF57_RS07905 (AAAF57_07945)	-	1727887..1728540 (-)	654	WP_410536485.1	DUF6287 domain-containing protein	-
AAAF57_RS07910 (AAAF57_07950)	-	1728638..1729957 (-)	1320	WP_410536487.1	sensor histidine kinase	-
AAAF57_RS07915 (AAAF57_07955)	comE/blpR	1729954..1730688 (-)	735	WP_155213913.1	response regulator transcription factor	Regulator
AAAF57_RS07920 (AAAF57_07960)	-	1730912..1733467 (-)	2556	WP_410536489.1	SH3 domain-containing protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28554.90 Da
• Isoelectric Point: 6.3900

>NTDB_id=972977 AAAF57_RS07915 WP_155213913.1 1729954..1730688(-) (comE/blpR) [Streptococcus salivarius strain KSS5]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENAKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLVNPENIIKLDKSTGTIYFENGGVCYVSKLKLKKLIE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=972977 AAAF57_RS07915 WP_155213913.1 1729954..1730688(-) (comE/blpR) [Streptococcus salivarius strain KSS5]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTAGGCGACTTTGAGGTTTTTGACAAACCCAATCAACTATTAGAGTCTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCTTGGATATTCAGATTAAAGATGATACTAAAAAAGGTTTGGAAGTGGCTAAGCAGATTCGAAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACCCATTCAGAGTATCTGCCCTTGACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGAGAGGATTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGCTAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTA
TACTTTGAGACATCAGACATTGTTCACAAGGTTATCCTTTATACCAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATCGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTGTCAATCCGGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACGATCTATTTTGAAAACGGCGGTGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGATTGAG
AGAATTAGTCTATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-123)

• LytTr DNA-binding domain (LytTR) (151-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.301	97.951	0.512
comE/comE1	Streptococcus equinus JB1	47.699	97.951	0.467
comE/comE2	Streptococcus equinus JB1	42.437	97.541	0.414
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.272	99.59	0.381
comE/comE2	Streptococcus gordonii strain NCTC7865	38.272	99.59	0.381
comE	Streptococcus pneumoniae TIGR4	38.174	98.77	0.377
comE	Streptococcus pneumoniae D39	38.174	98.77	0.377
comE	Streptococcus pneumoniae R6	38.174	98.77	0.377
comE	Streptococcus pneumoniae Rx1	38.174	98.77	0.377
comE	Streptococcus mitis SK321	38.174	98.77	0.377
comE	Streptococcus mitis NCTC 12261	38.174	98.77	0.377
comE	Streptococcus infantis strain Atu-4	37.759	98.77	0.373