Detailed information NTG0940705

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6U68_RS02270
• Genome accession: NZ_CP145866
• Coordinates: 439466..440200 (+)
• Length: 244 a.a.
• NCBI ID: WP_247925074.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 434466..445200

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS02245 (V6U68_02240)	-	434863..435654 (+)	792	WP_070654835.1	hypothetical protein	-
V6U68_RS02250 (V6U68_02245)	-	435651..436358 (+)	708	WP_073951043.1	hypothetical protein	-
V6U68_RS02255 (V6U68_02250)	-	436389..437072 (+)	684	WP_070654839.1	response regulator transcription factor	-
V6U68_RS02260 (V6U68_02255)	-	437057..438154 (+)	1098	WP_110981047.1	sensor histidine kinase	-
V6U68_RS02265 (V6U68_02260)	-	438369..439255 (-)	887	Protein_398	IS30 family transposase	-
V6U68_RS02270 (V6U68_02265)	comE/blpR	439466..440200 (+)	735	WP_247925074.1	response regulator transcription factor	Regulator
V6U68_RS02275 (V6U68_02270)	-	440671..441516 (+)	846	WP_410531827.1	sensor histidine kinase	-
V6U68_RS02280 (V6U68_02275)	-	441614..442267 (+)	654	WP_247925076.1	DUF6287 domain-containing protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28582.01 Da
• Isoelectric Point: 6.8395

>NTDB_id=940705 V6U68_RS02270 WP_247925074.1 439466..440200(+) (comE/blpR) [Streptococcus salivarius strain KSS9]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGKDFQKRVESIILLTCKKIQSQNPEDAFRIENVKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=940705 V6U68_RS02270 WP_247925074.1 439466..440200(+) (comE/blpR) [Streptococcus salivarius strain KSS9]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTGGGTGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTATTACCGAACGGGGGTCTC
ATCAGCTCTTTTTCTTGGACATTCAAATTAAAGACGATACTAAAAAAGGTTTGGAAGTGGCTAAGCAGATTCGCAAGAAT
GACCCCTATGCCAATATTGTTTTCTTCACGACCCATTCAGAGTATCTGCCCTTAACTTTTCAATACCAATTGGCAGCTCT
AGATTTTATTGATAAGTCTTTGGAGGGGAAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGATGCTTTTCGGATTGAGAATGTAAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATCGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-242)

• Response regulator receiver domain (Response_reg) (6-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	50.82	100	0.508
comE/comE1	Streptococcus equinus JB1	47.28	97.951	0.463
comE/comE2	Streptococcus equinus JB1	42.562	99.18	0.422
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.683	99.59	0.385
comE/comE2	Streptococcus gordonii strain NCTC7865	38.683	99.59	0.385
comE	Streptococcus infantis strain Atu-4	37.344	98.77	0.369
comE	Streptococcus pneumoniae D39	36.929	98.77	0.365
comE	Streptococcus pneumoniae R6	36.929	98.77	0.365
comE	Streptococcus pneumoniae Rx1	36.929	98.77	0.365
comE	Streptococcus mitis SK321	36.929	98.77	0.365
comE	Streptococcus mitis NCTC 12261	36.929	98.77	0.365
comE	Streptococcus pneumoniae TIGR4	36.929	98.77	0.365