Detailed information NTG0940704

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6U68_RS02210
• Genome accession: NZ_CP145866
• Coordinates: 429264..429998 (+)
• Length: 244 a.a.
• NCBI ID: WP_410531825.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 424264..434998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS02200 (V6U68_02195)	-	425395..426336 (+)	942	WP_410531822.1	hypothetical protein	-
V6U68_RS02205 (V6U68_02200)	-	426498..429053 (+)	2556	WP_410531824.1	SH3 domain-containing protein	-
V6U68_RS02210 (V6U68_02205)	comE/blpR	429264..429998 (+)	735	WP_410531825.1	response regulator transcription factor	Regulator
V6U68_RS02215 (V6U68_02210)	-	429995..431314 (+)	1320	WP_410531826.1	sensor histidine kinase	-
V6U68_RS02220 (V6U68_02215)	-	431412..432062 (+)	651	WP_247925072.1	DUF6287 domain-containing protein	-
V6U68_RS02225 (V6U68_02220)	-	432141..433081 (+)	941	Protein_390	IS3 family transposase	-
V6U68_RS02230 (V6U68_02225)	-	433222..433637 (-)	416	Protein_391	transposase	-
V6U68_RS02235 (V6U68_02230)	-	433854..433976 (+)	123	WP_148132219.1	putative RiPP precursor	-
V6U68_RS02240 (V6U68_02235)	-	434157..434873 (+)	717	WP_293935310.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28526.84 Da
• Isoelectric Point: 6.1626

>NTDB_id=940704 V6U68_RS02210 WP_410531825.1 429264..429998(+) (comE/blpR) [Streptococcus salivarius strain KSS9]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFQIENAKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=940704 V6U68_RS02210 WP_410531825.1 429264..429998(+) (comE/blpR) [Streptococcus salivarius strain KSS9]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTAGGCGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCTTGGACATTCAAATTAAAGACGATACTAAAAAAGGTTTGGAAGTGGCTAAGCAGATTCGCAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACCCATTCAGAGTATCTTCCCTTGACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCAGATTGAGAATGCTAAGACCGTTATTCAGGTTCCTTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATTGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-242)

• Response regulator receiver domain (Response_reg) (6-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	51.23	100	0.512
comE/comE1	Streptococcus equinus JB1	48.117	97.951	0.471
comE/comE2	Streptococcus equinus JB1	42.562	99.18	0.422
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.683	99.59	0.385
comE/comE2	Streptococcus gordonii strain NCTC7865	38.683	99.59	0.385
comE	Streptococcus infantis strain Atu-4	37.759	98.77	0.373
comE	Streptococcus pneumoniae D39	37.344	98.77	0.369
comE	Streptococcus pneumoniae R6	37.344	98.77	0.369
comE	Streptococcus pneumoniae Rx1	37.344	98.77	0.369
comE	Streptococcus mitis SK321	37.344	98.77	0.369
comE	Streptococcus mitis NCTC 12261	37.344	98.77	0.369
comE	Streptococcus pneumoniae TIGR4	37.344	98.77	0.369