Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   V6U67_RS09205 Genome accession   NZ_CP145865
Coordinates   1984726..1985667 (-) Length   313 a.a.
NCBI ID   WP_022496097.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS8     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1979726..1990667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS09165 (V6U67_09170) - 1979801..1980994 (-) 1194 WP_002885831.1 acetate kinase -
  V6U67_RS09170 (V6U67_09175) comYH 1981051..1982007 (-) 957 WP_022496101.1 class I SAM-dependent methyltransferase Machinery gene
  V6U67_RS09175 (V6U67_09180) comGG 1982052..1982369 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  V6U67_RS09180 (V6U67_09185) comYF 1982347..1982784 (-) 438 WP_022496100.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U67_RS09185 (V6U67_09190) comGE 1982771..1983001 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  V6U67_RS09190 (V6U67_09195) comYD 1983033..1983461 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U67_RS09195 (V6U67_09200) comYC 1983421..1983735 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U67_RS09200 (V6U67_09205) comYB 1983744..1984844 (-) 1101 WP_156024868.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U67_RS09205 (V6U67_09210) comYA 1984726..1985667 (-) 942 WP_022496097.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U67_RS09210 (V6U67_09215) - 1985747..1986109 (-) 363 WP_002887019.1 DUF1033 family protein -
  V6U67_RS09215 (V6U67_09220) rpoC 1986272..1989910 (-) 3639 WP_037603707.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35324.37 Da        Isoelectric Point: 5.7065

>NTDB_id=940678 V6U67_RS09205 WP_022496097.1 1984726..1985667(-) (comYA) [Streptococcus salivarius strain KSS8]
MVTEFAKEMIKNADSCGAQDIYVIPRQENYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTNWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=940678 V6U67_RS09205 WP_022496097.1 1984726..1985667(-) (comYA) [Streptococcus salivarius strain KSS8]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGAAAATTATGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCTACCGTAGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCTGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGCT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGATCCTGTGGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCATTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCCGAGTTGGATAATGCCCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAACTGGAACCAGCAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.495

100

0.655
  comYA Streptococcus mutans UA140

65.495

100

0.655
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

62.62

100

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361