Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6U67_RS02245 Genome accession   NZ_CP145865
Coordinates   438784..439518 (+) Length   244 a.a.
NCBI ID   WP_048676267.1    Uniprot ID   A0AAW6DBQ9
Organism   Streptococcus salivarius strain KSS8     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 433784..444518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS02240 (V6U67_02245) - 436018..438573 (+) 2556 WP_175061656.1 SH3 domain-containing protein -
  V6U67_RS02245 (V6U67_02250) comE/blpR 438784..439518 (+) 735 WP_048676267.1 response regulator transcription factor Regulator
  V6U67_RS02250 (V6U67_02255) - 439515..440834 (+) 1320 WP_272125993.1 sensor histidine kinase -
  V6U67_RS02255 (V6U67_02260) - 440932..441585 (+) 654 WP_155212855.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28554.90 Da        Isoelectric Point: 6.3900

>NTDB_id=940637 V6U67_RS02245 WP_048676267.1 438784..439518(+) (comE/blpR) [Streptococcus salivarius strain KSS8]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENAKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide


Download         Length: 735 bp        

>NTDB_id=940637 V6U67_RS02245 WP_048676267.1 438784..439518(+) (comE/blpR) [Streptococcus salivarius strain KSS8]
ATGCTTAACATCTATGTTTTAGAAGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAATATTAAAGTGGGGGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCTTGGACATTCAAATTAAAGACGATACTAAAAAAGGTTTGGAAGTGGCTAAGCAGATTCGCAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACCCATTCAGAGTATCTTCCCTTGACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGCTAAGACCGTTATTCAGGTTCCTTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATCGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-242)

Response regulator receiver domain (Response_reg)

(6-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.23

100

0.512
  comE/comE1 Streptococcus equinus JB1

48.117

97.951

0.471
  comE/comE2 Streptococcus equinus JB1

42.562

99.18

0.422
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.683

99.59

0.385
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.683

99.59

0.385
  comE Streptococcus infantis strain Atu-4

37.759

98.77

0.373
  comE Streptococcus pneumoniae D39

37.344

98.77

0.369
  comE Streptococcus pneumoniae R6

37.344

98.77

0.369
  comE Streptococcus pneumoniae Rx1

37.344

98.77

0.369
  comE Streptococcus mitis SK321

37.344

98.77

0.369
  comE Streptococcus mitis NCTC 12261

37.344

98.77

0.369
  comE Streptococcus pneumoniae TIGR4

37.344

98.77

0.369