Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6T01_RS02315 Genome accession   NZ_CP145856
Coordinates   444113..444847 (+) Length   244 a.a.
NCBI ID   WP_037599526.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS1     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 439113..449847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS02300 (V6T01_02290) - 439529..442111 (+) 2583 WP_410541198.1 SH3 domain-containing protein -
  V6T01_RS02305 (V6T01_02295) - 442313..443065 (+) 753 WP_037600457.1 response regulator transcription factor -
  V6T01_RS02310 (V6T01_02300) - 443201..443866 (+) 666 WP_037600454.1 DUF6287 domain-containing protein -
  V6T01_RS02315 (V6T01_02305) comE/blpR 444113..444847 (+) 735 WP_037599526.1 response regulator transcription factor Regulator
  V6T01_RS02320 (V6T01_02310) - 444844..446163 (+) 1320 WP_410541197.1 sensor histidine kinase -
  V6T01_RS02325 (V6T01_02315) - 446261..446914 (+) 654 WP_410541196.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28540.87 Da        Isoelectric Point: 6.3900

>NTDB_id=940171 V6T01_RS02315 WP_037599526.1 444113..444847(+) (comE/blpR) [Streptococcus salivarius strain KSS1]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESVTERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENAKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide


Download         Length: 735 bp        

>NTDB_id=940171 V6T01_RS02315 WP_037599526.1 444113..444847(+) (comE/blpR) [Streptococcus salivarius strain KSS1]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTGGGTGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTGTTACTGAGAGAGGATCTC
ATCAGCTCTTTTTCCTGGACATTCAGATTAAAGACGATACTAAAAAAGGCTTGGAAGTGGCTAAGCAGATTCGCAAGAAC
GACCCCTATGCCAATATTGTTTTCTTCACCACTCATTCAGAGTATCTTCCCTTGACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGCTAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATCGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-123)

LytTr DNA-binding domain (LytTR)

(151-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

50.82

100

0.508
  comE/comE1 Streptococcus equinus JB1

48.117

97.951

0.471
  comE/comE2 Streptococcus equinus JB1

42.562

99.18

0.422
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

39.095

99.59

0.389
  comE/comE2 Streptococcus gordonii strain NCTC7865

39.095

99.59

0.389
  comE Streptococcus infantis strain Atu-4

37.344

98.77

0.369
  comE Streptococcus pneumoniae D39

36.929

98.77

0.365
  comE Streptococcus pneumoniae R6

36.929

98.77

0.365
  comE Streptococcus pneumoniae Rx1

36.929

98.77

0.365
  comE Streptococcus mitis SK321

36.929

98.77

0.365
  comE Streptococcus mitis NCTC 12261

36.929

98.77

0.365
  comE Streptococcus pneumoniae TIGR4

36.929

98.77

0.365