Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Aeroheme_RS02355 Genome accession   NZ_CP144265
Coordinates   477294..478535 (-) Length   413 a.a.
NCBI ID   WP_106885656.1    Uniprot ID   A0AAP4J3C9
Organism   Aeromonas sp. DSM 116730     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 472294..483535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Aeroheme_RS02330 (Aeroheme_00471) mutT 474265..474669 (+) 405 WP_111911126.1 8-oxo-dGTP diphosphatase MutT -
  Aeroheme_RS02335 (Aeroheme_00472) yacG 474744..474938 (-) 195 WP_025328449.1 DNA gyrase inhibitor YacG -
  Aeroheme_RS02340 (Aeroheme_00473) zapD 474948..475670 (-) 723 WP_168235912.1 cell division protein ZapD -
  Aeroheme_RS02345 (Aeroheme_00474) coaE 475708..476322 (-) 615 WP_411166622.1 dephospho-CoA kinase -
  Aeroheme_RS02350 (Aeroheme_00475) pilD 476341..477213 (-) 873 WP_411166623.1 prepilin peptidase Machinery gene
  Aeroheme_RS02355 (Aeroheme_00476) pilC 477294..478535 (-) 1242 WP_106885656.1 type II secretion system F family protein Machinery gene
  Aeroheme_RS02360 (Aeroheme_00477) pilB 478666..480372 (-) 1707 WP_411166624.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  Aeroheme_RS02365 - 480376..480810 (-) 435 WP_395949385.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  Aeroheme_RS02370 (Aeroheme_00478) nadC 481123..481986 (-) 864 WP_411166625.1 carboxylating nicotinate-nucleotide diphosphorylase -
  Aeroheme_RS02375 (Aeroheme_00479) - 481990..482460 (-) 471 WP_171276940.1 TIGR02281 family clan AA aspartic protease -
  Aeroheme_RS02380 (Aeroheme_00480) ampD 482597..483169 (+) 573 WP_111911110.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45345.33 Da        Isoelectric Point: 9.9044

>NTDB_id=933066 Aeroheme_RS02355 WP_106885656.1 477294..478535(-) (pilC) [Aeromonas sp. DSM 116730]
MATLAQKQNAPKKVFSFRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQGQGMFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSDALRRHPRHFDALYCDLVEAGEQSGALETIYDRI
AIYREKSEALKSKIKKAMFYPAMVILVAIIVTSILLLFVIPQFEEIFKSFGAELPAFTRFIIAISRFMQDWWYAIFGGIA
LTVFLYVRAWRSSQKVRDNTDKFILSIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATLAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=933066 Aeroheme_RS02355 WP_106885656.1 477294..478535(-) (pilC) [Aeromonas sp. DSM 116730]
ATGGCAACATTAGCTCAAAAACAGAATGCACCAAAAAAGGTCTTCTCCTTCCGCTGGCACGGCGTCAATCGCAAGGGACA
AAAGGTTTCCGGTGAGTTGCAGGCCGACAGCATCACGACCGTCAAGGCGGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
GGGTCAGCAAGCAGGGCCAGGGGATGTTTTCCAAGGGCGGCGCCAGGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGTGTGCCGCTAGTGCAGAGCCTGCAGATCATCGCCCGCGGCCACGAAAAAGCAGC
GGTGCGCGAGCTGATCGGCCAGATCGCCGCCGATGTGGAGACAGGCACCCCACTGTCGGATGCGCTGCGCCGCCATCCCC
GCCACTTCGATGCCCTCTACTGTGACCTGGTGGAAGCGGGGGAACAGTCAGGCGCGCTGGAAACCATCTACGACCGGATT
GCCATCTATCGCGAAAAGAGCGAGGCGCTCAAATCCAAAATAAAGAAGGCCATGTTCTATCCCGCCATGGTCATCCTGGT
CGCCATCATAGTGACCTCCATACTGTTGCTGTTCGTCATCCCCCAGTTCGAAGAGATCTTCAAGAGCTTCGGGGCCGAGC
TGCCTGCCTTCACCCGATTCATCATTGCCATCTCCCGCTTCATGCAGGATTGGTGGTACGCCATCTTCGGCGGCATAGCC
CTGACAGTGTTCCTCTATGTGCGCGCCTGGCGCAGCTCCCAGAAGGTACGTGACAACACCGACAAGTTCATCCTCTCCAT
TCCGGTCGTTGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TTCCCCTGGTGGATGCCCTGGTCTCCGCTGCCGGGGCCTCGGGCAACTATGTCTATCGCACGGCTACCCTGGCCATACGC
AACGAGGTCGTGGCTGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTGTTCCCCGACATGGTGATCCAGATGGT
GATGATAGGTGAAGAGTCCGGCGCCATCGACGACATGCTCTCCAAGGTAGCCGCCATCTTCGAGCAGGAGGTGGACGACA
TGGTCGATGGTCTCACCAGCCTGCTCGAGCCCATCATAATGGTGGTGCTGGGGGTGCTGGTCGGCGGCATGGTCGTCGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

55.303

95.884

0.53
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baumannii D1279779

51.87

97.094

0.504
  pilC Acinetobacter baylyi ADP1

50.882

96.126

0.489
  pilC Vibrio cholerae strain A1552

46.192

98.547

0.455
  pilC Vibrio campbellii strain DS40M4

44.802

97.821

0.438
  pilG Neisseria meningitidis 44/76-A

40.247

98.063

0.395
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilC Thermus thermophilus HB27

38

96.852

0.368