Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MWM02_RS12860 Genome accession   NZ_AP025627
Coordinates   2557415..2558662 (-) Length   415 a.a.
NCBI ID   WP_244402187.1    Uniprot ID   -
Organism   Parageobacillus sp. KH3-4     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 2552415..2563662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM02_RS12840 (PspKH34_25350) spoVS 2552896..2553156 (-) 261 WP_003251598.1 stage V sporulation protein SpoVS -
  MWM02_RS12845 (PspKH34_25360) - 2553282..2554076 (-) 795 WP_064550966.1 TIGR00282 family metallophosphoesterase -
  MWM02_RS12850 (PspKH34_25370) rny 2554160..2555725 (-) 1566 WP_064550967.1 ribonuclease Y -
  MWM02_RS12855 (PspKH34_25380) recA 2556197..2557249 (-) 1053 WP_064551284.1 recombinase RecA Machinery gene
  MWM02_RS12860 (PspKH34_25390) cinA 2557415..2558662 (-) 1248 WP_244402187.1 competence/damage-inducible protein A Machinery gene
  MWM02_RS12865 (PspKH34_25400) pgsA 2558776..2559354 (-) 579 WP_064550969.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MWM02_RS12870 (PspKH34_25410) - 2559409..2560284 (-) 876 WP_244402188.1 helix-turn-helix domain-containing protein -
  MWM02_RS12875 (PspKH34_25420) - 2560315..2561106 (-) 792 WP_064550971.1 DUF3388 domain-containing protein -
  MWM02_RS12880 (PspKH34_25430) - 2561246..2561494 (-) 249 WP_064550972.1 DUF3243 domain-containing protein -
  MWM02_RS12885 (PspKH34_25440) - 2561557..2562273 (-) 717 WP_064550973.1 SDR family oxidoreductase -
  MWM02_RS12890 (PspKH34_25450) - 2562313..2563605 (-) 1293 WP_064550974.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45105.14 Da        Isoelectric Point: 8.1353

>NTDB_id=93296 MWM02_RS12860 WP_244402187.1 2557415..2558662(-) (cinA) [Parageobacillus sp. KH3-4]
MNAEIIAVGSELLLGQIANTNAQFLSAQLAELGINVYFHTVVGDNAARLEKAVKVAQTRANLIIFTGGLGPTKDDLTKET
IARLLGRELVIDKEALHSIEAYFARTGRTMTENNKKQALVLQGSTVLRNEHGMAPGMAMTIDSITYMLLPGPPKEMQPMF
IKYGRPFLMEKLDRHERIESRVLRFFGIGESQLETEIEDLIEQQSNPTIAPLAGDGEVTLRLTAKHHSEIEAKKLLDKTE
QAILARVGRYFYGYNDETLFKNAVKMLKEKKKTIAAAESLTGGLFLTELTAIPGASQVVRGGVVCYANEVKEKVLRVPAS
VLATDGAVSERCAKLLAENVRTLCHADIGISFTGVAGPDPLEGKPVGTVYIGISTSENKTDVYALALSGQRDAIRIRTAK
HGCSIILKTLAAARS

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=93296 MWM02_RS12860 WP_244402187.1 2557415..2558662(-) (cinA) [Parageobacillus sp. KH3-4]
TTGAACGCGGAAATTATCGCTGTTGGCTCCGAATTGTTGCTTGGGCAGATCGCTAACACGAATGCGCAGTTTTTATCTGC
CCAGCTCGCCGAACTTGGCATTAACGTATATTTTCATACTGTTGTAGGCGACAATGCTGCCCGTCTGGAAAAAGCGGTAA
AAGTGGCACAAACACGGGCGAATTTAATTATTTTCACAGGCGGACTTGGTCCAACGAAAGATGATTTAACAAAAGAGACG
ATTGCCCGCCTATTGGGGCGAGAGCTTGTCATTGACAAGGAAGCGCTTCATTCCATCGAAGCGTATTTTGCCCGCACAGG
CCGAACGATGACAGAAAACAATAAAAAGCAGGCGCTTGTATTGCAAGGCTCCACTGTATTGAGAAACGAACACGGAATGG
CGCCTGGAATGGCAATGACGATCGATTCGATTACGTACATGCTTCTCCCTGGTCCGCCAAAGGAAATGCAGCCGATGTTC
ATCAAATACGGCCGCCCGTTCTTAATGGAGAAGCTTGACCGCCATGAGCGCATTGAATCGCGTGTGCTACGCTTTTTCGG
AATCGGTGAATCGCAGCTTGAAACGGAAATCGAAGATCTTATTGAGCAACAGTCAAATCCGACGATTGCCCCTCTTGCCG
GCGATGGGGAAGTAACGCTGCGCTTGACAGCGAAACACCATTCTGAAATCGAAGCCAAAAAGCTTCTTGATAAAACCGAA
CAAGCGATTTTAGCGCGCGTCGGCCGCTATTTTTATGGCTACAACGATGAAACGCTGTTTAAAAATGCCGTGAAGATGTT
GAAGGAAAAAAAGAAAACGATCGCGGCTGCCGAAAGCCTCACTGGCGGGCTTTTCTTAACGGAATTAACGGCCATTCCCG
GCGCTTCCCAAGTGGTTCGCGGCGGGGTCGTCTGCTATGCCAATGAAGTAAAGGAGAAAGTTCTTCGCGTTCCCGCTTCT
GTGTTGGCAACCGACGGAGCGGTAAGCGAACGCTGCGCAAAGCTGTTGGCGGAAAATGTCCGCACGCTTTGCCATGCGGA
TATTGGCATTAGTTTTACAGGCGTGGCAGGACCGGACCCGCTTGAAGGGAAACCAGTCGGTACCGTATATATTGGTATTT
CCACCTCTGAAAATAAAACAGACGTCTACGCCCTCGCATTATCCGGCCAGCGTGATGCGATTCGCATTCGCACTGCGAAA
CACGGCTGCTCCATTATATTAAAAACATTGGCAGCTGCACGTTCGTAG

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(257-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

60.294

98.313

0.593
  cinA Streptococcus mitis SK321

48.095

100

0.487
  cinA Streptococcus mutans UA159

47.733

100

0.482
  cinA Streptococcus mitis NCTC 12261

47.619

100

0.482
  cinA Streptococcus pneumoniae TIGR4

47.143

100

0.477
  cinA Streptococcus pneumoniae Rx1

47.143

100

0.477
  cinA Streptococcus pneumoniae R6

47.143

100

0.477
  cinA Streptococcus pneumoniae D39

46.905

100

0.475
  cinA Streptococcus suis isolate S10

43.272

91.325

0.395

Multiple sequence alignment