Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   VP472_RS11685 Genome accession   NZ_CP143632
Coordinates   2422986..2423786 (-) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus sp. MT(2024)     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 2417986..2428786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP472_RS11655 (VP472_11655) - 2418532..2419164 (+) 633 WP_014418348.1 helix-turn-helix domain-containing protein -
  VP472_RS11660 (VP472_11660) - 2419455..2419592 (+) 138 WP_014470646.1 hypothetical protein -
  VP472_RS11665 (VP472_11665) - 2419686..2420804 (+) 1119 WP_003153184.1 NADH-dependent flavin oxidoreductase -
  VP472_RS11670 (VP472_11670) - 2420931..2421143 (+) 213 WP_003153183.1 spore germination protein -
  VP472_RS11675 (VP472_11675) - 2421270..2421482 (+) 213 WP_014305392.1 spore germination protein -
  VP472_RS11680 (VP472_11680) alr 2421657..2422838 (+) 1182 WP_146277153.1 alanine racemase -
  VP472_RS11685 (VP472_11685) spo0A 2422986..2423786 (-) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  VP472_RS11690 (VP472_11690) spoIVB 2424067..2425347 (-) 1281 WP_007408360.1 SpoIVB peptidase -
  VP472_RS11695 (VP472_11695) recN 2425511..2427241 (-) 1731 WP_146277155.1 DNA repair protein RecN Machinery gene
  VP472_RS11700 (VP472_11700) argR 2427273..2427722 (-) 450 WP_003153173.1 transcriptional regulator ArgR -
  VP472_RS11705 (VP472_11705) - 2427817..2428662 (-) 846 WP_003153172.1 TlyA family RNA methyltransferase -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=930034 VP472_RS11685 WP_003153177.1 2422986..2423786(-) (spo0A) [Bacillus sp. MT(2024)]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=930034 VP472_RS11685 WP_003153177.1 2422986..2423786(-) (spo0A) [Bacillus sp. MT(2024)]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCCGATGTGCTCG
TTTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCGC
CGTCCGCGCAAAGCAGCATTATCCGCAGCCAGCCGGAGCCGAAACGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTACCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACCGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATTTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAACCAACCAACTCGGAATTCATCGCGATGGTTGCTGACAAGCTGAGATTGGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97