Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   V1235_RS04260 Genome accession   NZ_CP143348
Coordinates   916100..918532 (+) Length   810 a.a.
NCBI ID   WP_000472705.1    Uniprot ID   A0A231SZ39
Organism   Acinetobacter baumannii strain 2023CK-01512     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 915328..929364 916100..918532 within 0


Gene organization within MGE regions


Location: 915328..929364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V1235_RS04255 (V1235_04255) lolD 915328..916014 (+) 687 WP_000049403.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  V1235_RS04260 (V1235_04260) comA/comEC 916100..918532 (+) 2433 WP_000472705.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V1235_RS04265 (V1235_04265) - 918485..919468 (-) 984 WP_001984639.1 lysophospholipid acyltransferase family protein -
  V1235_RS04270 (V1235_04270) sppA 919605..920621 (+) 1017 WP_001286615.1 signal peptide peptidase SppA -
  V1235_RS04275 (V1235_04275) - 920640..921449 (+) 810 WP_000114076.1 alpha/beta hydrolase -
  V1235_RS04280 (V1235_04280) purN 921513..922142 (-) 630 WP_000975536.1 phosphoribosylglycinamide formyltransferase -
  V1235_RS04285 (V1235_04285) purM 922139..923209 (-) 1071 WP_000071984.1 phosphoribosylformylglycinamidine cyclo-ligase -
  V1235_RS04290 (V1235_04290) cxpE 923345..924538 (+) 1194 WP_001153980.1 chloramphenicol efflux transporter CxpE -
  V1235_RS04295 (V1235_04295) hda 924559..925257 (+) 699 WP_001249535.1 DnaA regulatory inactivator Hda -
  V1235_RS04300 (V1235_04300) rbtA 925574..927424 (+) 1851 WP_000920012.1 rhombotarget A -
  V1235_RS04305 (V1235_04305) - 927440..928378 (+) 939 Protein_821 CSLREA domain-containing protein -
  V1235_RS04310 (V1235_04310) - 928432..929364 (-) 933 WP_001043692.1 IS5-like element ISAba13 family transposase -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 92426.69 Da        Isoelectric Point: 8.6357

>NTDB_id=928814 V1235_RS04260 WP_000472705.1 916100..918532(+) (comA/comEC) [Acinetobacter baumannii strain 2023CK-01512]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNFSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSAFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQQFL
SLSSKMIFMGKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFIVKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=928814 V1235_RS04260 WP_000472705.1 916100..918532(+) (comA/comEC) [Acinetobacter baumannii strain 2023CK-01512]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGACCAATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATTTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAATGGTTTATTCAGCGAAATATTATGTCTGGTTTTAATGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACAGTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGGGTAAGGTGTTAATTGAGTCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTATAGTAAAACCGTTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAACAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCAGGATGGGAAGCCGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(33-188)

Metallo-beta-lactamase superfamily (Lactamase_B)

(555-639)

Competence protein (Competence)

(243-521)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A231SZ39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Acinetobacter baumannii D1279779

98.025

100

0.98
  comA/comEC Acinetobacter baumannii strain A118

97.037

100

0.97
  comA/comEC Acinetobacter baylyi ADP1

50.246

100

0.504