Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   VKP56_RS00650 Genome accession   NZ_CP142350
Coordinates   102124..103062 (+) Length   312 a.a.
NCBI ID   WP_326657116.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1445     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97124..108062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP56_RS00640 (VKP56_00640) rpoC 97873..101514 (+) 3642 WP_032460334.1 DNA-directed RNA polymerase subunit beta' -
  VKP56_RS00645 (VKP56_00645) - 101666..102031 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP56_RS00650 (VKP56_00650) comYA 102124..103062 (+) 939 WP_326657116.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP56_RS00655 (VKP56_00655) comYB 102998..104032 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP56_RS00660 (VKP56_00660) comYC 104034..104360 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP56_RS00665 (VKP56_00665) comGD 104335..104763 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP56_RS00670 (VKP56_00670) comGE 104720..105004 (+) 285 WP_265415305.1 competence type IV pilus minor pilin ComGE -
  VKP56_RS00675 (VKP56_00675) comYF 104997..105431 (+) 435 WP_326657121.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP56_RS00680 (VKP56_00680) comGG 105415..105741 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP56_RS00685 (VKP56_00685) comYH 105839..106792 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  VKP56_RS00690 (VKP56_00690) - 106851..108047 (+) 1197 WP_011284424.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35089.37 Da        Isoelectric Point: 8.5799

>NTDB_id=924972 VKP56_RS00650 WP_326657116.1 102124..103062(+) (comYA) [Streptococcus pyogenes strain SS1445]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLVSHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGLVGSGKTTLMYQLISNYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YVRLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=924972 VKP56_RS00650 WP_326657116.1 102124..103062(+) (comYA) [Streptococcus pyogenes strain SS1445]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTGTTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTCAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACTAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGTAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

60.772

99.679

0.606
  comYA Streptococcus mutans UA159

60.772

99.679

0.606
  comYA Streptococcus gordonii str. Challis substr. CH1

60.129

99.679

0.599
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

59.677

99.359

0.593
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.199

99.679

0.58
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.199

99.679

0.58
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.199

99.679

0.58
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.199

99.679

0.58
  comGA Lactococcus lactis subsp. cremoris KW2

50.161

99.679

0.5
  comGA Latilactobacillus sakei subsp. sakei 23K

38.966

92.949

0.362