Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   VKP56_RS00675 Genome accession   NZ_CP142350
Coordinates   104997..105431 (+) Length   144 a.a.
NCBI ID   WP_326657121.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1445     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99997..110431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP56_RS00645 (VKP56_00645) - 101666..102031 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP56_RS00650 (VKP56_00650) comYA 102124..103062 (+) 939 WP_326657116.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP56_RS00655 (VKP56_00655) comYB 102998..104032 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP56_RS00660 (VKP56_00660) comYC 104034..104360 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP56_RS00665 (VKP56_00665) comGD 104335..104763 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP56_RS00670 (VKP56_00670) comGE 104720..105004 (+) 285 WP_265415305.1 competence type IV pilus minor pilin ComGE -
  VKP56_RS00675 (VKP56_00675) comYF 104997..105431 (+) 435 WP_326657121.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP56_RS00680 (VKP56_00680) comGG 105415..105741 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP56_RS00685 (VKP56_00685) comYH 105839..106792 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  VKP56_RS00690 (VKP56_00690) - 106851..108047 (+) 1197 WP_011284424.1 acetate kinase -
  VKP56_RS00695 (VKP56_00695) - 108234..108542 (+) 309 WP_030126458.1 hypothetical protein -
  VKP56_RS00700 (VKP56_00700) proC 108625..109395 (-) 771 WP_014407219.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16598.23 Da        Isoelectric Point: 10.2064

>NTDB_id=924975 VKP56_RS00675 WP_326657121.1 104997..105431(+) (comYF) [Streptococcus pyogenes strain SS1445]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERNFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=924975 VKP56_RS00675 WP_326657121.1 104997..105431(+) (comYF) [Streptococcus pyogenes strain SS1445]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGAATTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

50.36

96.528

0.486
  comYF Streptococcus mutans UA159

49.64

96.528

0.479
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

44.776

93.056

0.417
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396