Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   OCV52_RS12980 Genome accession   NZ_AP025465
Coordinates   2856662..2857891 (+) Length   409 a.a.
NCBI ID   WP_137409079.1    Uniprot ID   A0A7V7NPJ8
Organism   Vibrio chagasii strain LMG 21353     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2851662..2862891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCV52_RS12960 ampD 2852669..2853268 (-) 600 WP_137409076.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  OCV52_RS12965 nadC 2853352..2854242 (+) 891 WP_137409077.1 carboxylating nicotinate-nucleotide diphosphorylase -
  OCV52_RS12970 - 2854497..2854961 (+) 465 WP_137409082.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  OCV52_RS12975 pilB 2854961..2856646 (+) 1686 WP_137409078.1 type IV-A pilus assembly ATPase PilB Machinery gene
  OCV52_RS12980 pilC 2856662..2857891 (+) 1230 WP_137409079.1 type II secretion system F family protein Machinery gene
  OCV52_RS12985 pilD 2857958..2858827 (+) 870 WP_137409080.1 A24 family peptidase Machinery gene
  OCV52_RS12990 coaE 2858830..2859444 (+) 615 WP_061032470.1 dephospho-CoA kinase -
  OCV52_RS12995 zapD 2859471..2860211 (+) 741 WP_061032469.1 cell division protein ZapD -
  OCV52_RS13000 yacG 2860292..2860489 (+) 198 WP_008222354.1 DNA gyrase inhibitor YacG -
  OCV52_RS13005 - 2861160..2861966 (-) 807 WP_261900850.1 IS110 family transposase -
  OCV52_RS13010 - 2861988..2862185 (-) 198 WP_261900851.1 hypothetical protein -
  OCV52_RS13015 rplS 2862361..2862714 (-) 354 WP_004738151.1 50S ribosomal protein L19 -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45299.33 Da        Isoelectric Point: 10.0799

>NTDB_id=91741 OCV52_RS12980 WP_137409079.1 2856662..2857891(+) (pilC) [Vibrio chagasii strain LMG 21353]
MITKPKQSQLKSYHWKGINSSGKKVSGQTLALTELEVREKLKDQHIQIKKIKKKSISALTRLTHRVKSRDITVLTRQLAT
MLGTGVPIVQAIKLVSDNHRKAEMKSILSHICKGVEAGTPISKAMRTASRHFDDLYTDLVATGELSGNLAQVFERLATYR
EKSEQLKSKVIKALIYPAMVVTVALTVSYLMLTMVIPEFESMFSGFGADLPWFTQQVLELSHWMQAYSFYTFVGAGLAAL
VIYQLCQRSYSIRLSTSRLGLRFPILGGVMAKASIAKFSRTLSTSFGSGIPILMSLKTTAKTAGNLHYESAIIEVHRETA
AGIPMYIAMRNTNAFPEMMLQMVMIGEESGNLDEMLNKIASIYEFEVDNTVDNLGKILEPLIIVFLGSVVGGLVVAMYLP
IFNLMSVLG

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=91741 OCV52_RS12980 WP_137409079.1 2856662..2857891(+) (pilC) [Vibrio chagasii strain LMG 21353]
ATGATCACTAAACCTAAGCAATCACAATTAAAAAGCTACCACTGGAAAGGCATCAACAGCTCTGGCAAAAAAGTGTCAGG
GCAGACCTTAGCGCTTACTGAATTAGAGGTGCGTGAAAAGCTCAAAGATCAGCATATCCAGATAAAGAAAATCAAAAAGA
AAAGTATTTCGGCACTGACGCGTTTAACCCATCGAGTTAAATCTAGAGACATCACCGTGTTGACCCGCCAGCTTGCTACC
ATGCTAGGAACTGGCGTCCCAATCGTGCAGGCGATTAAATTGGTCTCAGATAACCACCGCAAAGCTGAAATGAAATCTAT
CCTGTCACACATATGTAAAGGTGTCGAAGCTGGTACACCTATCTCCAAAGCGATGCGAACCGCGAGTCGCCACTTTGATG
ATCTTTATACCGATTTAGTCGCAACGGGTGAGCTCTCGGGTAACCTTGCGCAAGTATTTGAACGCCTAGCGACATATCGA
GAGAAGAGTGAACAGCTCAAGTCTAAGGTCATCAAAGCGCTCATCTATCCTGCAATGGTGGTTACTGTCGCACTCACAGT
CTCTTATTTAATGCTGACCATGGTGATTCCTGAGTTTGAGTCGATGTTTTCGGGCTTTGGTGCCGACCTCCCTTGGTTTA
CTCAGCAAGTACTTGAGCTTTCTCATTGGATGCAGGCATACAGCTTTTACACGTTTGTAGGTGCTGGGTTGGCTGCCTTA
GTAATCTATCAACTCTGTCAGCGCTCCTACTCGATTCGATTATCTACCAGCCGCTTAGGATTAAGGTTTCCAATCCTAGG
CGGAGTAATGGCCAAAGCCTCCATTGCCAAGTTCAGTCGAACACTATCAACCAGTTTCGGTTCTGGTATCCCCATTCTCA
TGAGCCTAAAAACCACGGCCAAAACCGCAGGCAACCTGCACTATGAATCGGCAATCATTGAAGTACATCGTGAAACCGCT
GCGGGCATCCCTATGTATATTGCCATGCGTAATACCAATGCGTTTCCTGAAATGATGTTGCAGATGGTGATGATTGGCGA
AGAGTCTGGAAACCTTGATGAAATGCTCAACAAAATCGCCTCGATTTACGAGTTTGAAGTAGACAACACCGTCGACAATT
TAGGCAAAATATTAGAGCCGCTGATCATTGTGTTTTTAGGATCTGTAGTGGGTGGTCTTGTGGTTGCGATGTACTTACCG
ATCTTTAATCTTATGAGTGTGTTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(75-197)

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7V7NPJ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

79.5

97.8

0.778
  pilC Vibrio campbellii strain DS40M4

73.201

98.533

0.721
  pilC Acinetobacter baumannii D1279779

41.337

98.778

0.408
  pilC Acinetobacter baylyi ADP1

42.065

97.066

0.408
  pilC Legionella pneumophila strain ERS1305867

41.353

97.555

0.403
  pilG Neisseria gonorrhoeae MS11

40.602

97.555

0.396
  pilC Pseudomonas stutzeri DSM 10701

40.657

96.822

0.394
  pilG Neisseria meningitidis 44/76-A

40.351

97.555

0.394

Multiple sequence alignment