Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   U8518_RS21600 Genome accession   NZ_CP141267
Coordinates   4704467..4705708 (-) Length   413 a.a.
NCBI ID   WP_101149982.1    Uniprot ID   -
Organism   Aeromonas hydrophila strain MaAh001     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4699467..4710708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8518_RS21570 (U8518_21570) - 4700307..4701492 (+) 1186 Protein_4169 tetratricopeptide repeat protein -
  U8518_RS21575 (U8518_21575) mutT 4701501..4701914 (+) 414 WP_180807567.1 8-oxo-dGTP diphosphatase MutT -
  U8518_RS21580 (U8518_21580) yacG 4701975..4702169 (-) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  U8518_RS21585 (U8518_21585) zapD 4702179..4702901 (-) 723 WP_180807569.1 cell division protein ZapD -
  U8518_RS21590 (U8518_21590) coaE 4702939..4703553 (-) 615 WP_101149980.1 dephospho-CoA kinase -
  U8518_RS21595 (U8518_21595) pilD 4703572..4704444 (-) 873 WP_101149981.1 prepilin peptidase Machinery gene
  U8518_RS21600 (U8518_21600) pilC 4704467..4705708 (-) 1242 WP_101149982.1 type II secretion system F family protein Machinery gene
  U8518_RS21605 (U8518_21605) pilB 4705824..4707539 (-) 1716 WP_180807586.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  U8518_RS21610 (U8518_21610) - 4707530..4707970 (-) 441 WP_043160631.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  U8518_RS21615 (U8518_21615) nadC 4708293..4709150 (-) 858 WP_101149983.1 carboxylating nicotinate-nucleotide diphosphorylase -
  U8518_RS21620 (U8518_21620) - 4709156..4709626 (-) 471 WP_101149984.1 TIGR02281 family clan AA aspartic protease -
  U8518_RS21625 (U8518_21625) ampD 4709773..4710345 (+) 573 WP_101149985.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45438.62 Da        Isoelectric Point: 9.9428

>NTDB_id=916734 U8518_RS21600 WP_101149982.1 4704467..4705708(-) (pilC) [Aeromonas hydrophila strain MaAh001]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTKFVIGISRFMQNWWYVIFGGIA
LSIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=916734 U8518_RS21600 WP_101149982.1 4704467..4705708(-) (pilC) [Aeromonas hydrophila strain MaAh001]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAGCAAGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCGCTGCGCCGTCATCCCC
GCCACTTTGACGATCTTTACTGCGATCTGGTGGAGGCTGGTGAACAATCCGGCGCCCTAGAGACCATCTACGATCGCATC
GCTACCTATCGCGAAAAATCGGAAGCACTCAAGTCCAAGATCAAGAAAGCCATGTTTTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTTACCTCCATTCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGTGCCGAAC
TGCCCATCTTCACTAAGTTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTTTCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCACGTTTCGCCCGTACCCTCTCCACGACCTTCTCTGCCGGTA
TCCCGCTGGTGGATGCCTTGGTTTCTGCAGCTGGCGCCTCCGGCAACTATGTCTACCGTACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAAATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGGTCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.071

95.884

0.547
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

51.637

96.126

0.496
  pilC Vibrio cholerae strain A1552

47.487

96.368

0.458
  pilC Vibrio campbellii strain DS40M4

46.096

96.126

0.443
  pilG Neisseria gonorrhoeae MS11

39.753

98.063

0.39
  pilG Neisseria meningitidis 44/76-A

39.506

98.063

0.387
  pilC Thermus thermophilus HB27

37.75

96.852

0.366