Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SM121_RS01100 Genome accession   NZ_CP139418
Coordinates   226367..227308 (-) Length   313 a.a.
NCBI ID   WP_155127112.1    Uniprot ID   A0A6A8V6X9
Organism   Streptococcus dentalis strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 221367..232308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS01065 (SM121_01065) comYH 222592..223545 (-) 954 WP_155127115.1 class I SAM-dependent methyltransferase Machinery gene
  SM121_RS01070 (SM121_01070) comGG 223576..224013 (-) 438 WP_320910982.1 competence type IV pilus minor pilin ComGG -
  SM121_RS01075 (SM121_01075) comGF/cglF 224000..224452 (-) 453 WP_151190960.1 competence type IV pilus minor pilin ComGF Machinery gene
  SM121_RS01080 (SM121_01080) comGE 224442..224729 (-) 288 WP_003004353.1 competence type IV pilus minor pilin ComGE -
  SM121_RS01085 (SM121_01085) comYD 224695..225099 (-) 405 WP_003004513.1 competence type IV pilus minor pilin ComGD Machinery gene
  SM121_RS01090 (SM121_01090) comYC 225089..225406 (-) 318 WP_003013558.1 competence type IV pilus major pilin ComGC Machinery gene
  SM121_RS01095 (SM121_01095) comYB 225403..226434 (-) 1032 WP_320911301.1 competence type IV pilus assembly protein ComGB Machinery gene
  SM121_RS01100 (SM121_01100) comYA 226367..227308 (-) 942 WP_155127112.1 competence type IV pilus ATPase ComGA Machinery gene
  SM121_RS01105 (SM121_01105) - 227396..227785 (-) 390 WP_037615753.1 DUF1033 family protein -
  SM121_RS01110 (SM121_01110) - 228007..229110 (-) 1104 WP_320910983.1 glycosyl hydrolase family 8 -
  SM121_RS01115 (SM121_01115) - 229119..230429 (-) 1311 WP_003004511.1 glycosyltransferase -
  SM121_RS01120 (SM121_01120) - 230422..230562 (-) 141 WP_003004308.1 hypothetical protein -
  SM121_RS01125 (SM121_01125) - 230572..231360 (-) 789 WP_003004116.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35827.08 Da        Isoelectric Point: 6.2604

>NTDB_id=909472 SM121_RS01100 WP_155127112.1 226367..227308(-) (comYA) [Streptococcus dentalis strain S1]
MVQEIAKKLIRLGKKEEAQDLYFIPRKEEYQVFMRVGDERRFVQSFPFEDMTAIISHFKFAAGMNVGEKRRSQLGSCDYP
LEDGVVSIRLSTVGDYRGYESLVIRLLHDEERELRFWFDQLPDLQKKLAGRGLYLFAGPVGSGKTTLMHALAQERFADQQ
VMSIEDPVEIKQENMLQLQLNDQIGMTYDNLIKLSLRHRPDLLIIGEIRDKETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVSEEELKTVLQGICYQRLIAGGGVVDFATENYQEHSASRWNQQMDLLAQSGYIQLAQAQAEKIIYR

Nucleotide


Download         Length: 942 bp        

>NTDB_id=909472 SM121_RS01100 WP_155127112.1 226367..227308(-) (comYA) [Streptococcus dentalis strain S1]
ATGGTTCAAGAAATTGCAAAAAAATTGATCCGCCTGGGGAAAAAGGAAGAAGCTCAGGATCTTTACTTCATTCCTCGGAA
GGAGGAGTACCAGGTTTTTATGAGGGTGGGAGATGAGAGACGTTTTGTACAGTCCTTCCCTTTTGAGGACATGACAGCTA
TTATTAGCCACTTCAAATTTGCAGCAGGGATGAATGTAGGAGAAAAAAGGCGCAGCCAGCTAGGATCGTGTGATTACCCA
TTAGAGGATGGAGTGGTTTCGATTCGCTTGTCGACAGTGGGGGATTATCGTGGCTATGAAAGCTTGGTCATTCGGCTCTT
GCATGATGAGGAACGTGAATTGCGGTTTTGGTTTGACCAGTTGCCGGACTTGCAGAAGAAATTGGCTGGTCGTGGGCTTT
ATCTTTTTGCGGGTCCCGTTGGCTCGGGAAAGACCACTCTCATGCATGCGTTGGCGCAAGAGCGCTTTGCGGACCAGCAA
GTCATGTCCATTGAAGATCCTGTCGAGATCAAGCAAGAGAATATGCTTCAGCTCCAGCTGAATGACCAGATCGGCATGAC
CTATGACAACCTGATCAAACTCTCCTTGCGCCATCGGCCGGACCTTCTCATTATTGGAGAAATCCGAGATAAGGAAACAG
CTCGTGCAGTCGTACGAGCTAGTTTGACAGGAGTCACCGTCTTCTCTACTATTCATGCCAAGAGCGTTCGAGGTGTTTAT
GAGAGGCTCTTAGAACTTGGAGTGAGCGAGGAAGAGCTCAAGACAGTTTTACAAGGTATTTGCTACCAACGATTAATTGC
AGGAGGAGGTGTGGTCGATTTTGCGACGGAAAACTACCAAGAGCACTCAGCCAGCCGCTGGAACCAACAAATGGATCTCT
TGGCTCAATCGGGATATATCCAGCTGGCTCAGGCGCAAGCCGAAAAAATTATCTACCGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(15-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6A8V6X9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

73.871

99.042

0.732
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

71.154

99.681

0.709
  comGA/cglA/cilD Streptococcus pneumoniae D39

70.833

99.681

0.706
  comGA/cglA/cilD Streptococcus pneumoniae R6

70.833

99.681

0.706
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

70.833

99.681

0.706
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

70.833

99.681

0.706
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.446

88.818

0.377