Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   L6424_RS02630 Genome accession   NZ_AP025277
Coordinates   564119..565360 (-) Length   413 a.a.
NCBI ID   WP_011707570.1    Uniprot ID   A0KPV8
Organism   Aeromonas hydrophila strain NUITM-VA1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 559119..570360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6424_RS02600 (NUITMVA1_04980) - 559959..561143 (+) 1185 WP_024945433.1 tetratricopeptide repeat protein -
  L6424_RS02605 (NUITMVA1_04990) mutT 561152..561565 (+) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  L6424_RS02610 (NUITMVA1_05000) yacG 561626..561820 (-) 195 WP_024945432.1 DNA gyrase inhibitor YacG -
  L6424_RS02615 (NUITMVA1_05010) zapD 561830..562552 (-) 723 WP_024945431.1 cell division protein ZapD -
  L6424_RS02620 (NUITMVA1_05020) coaE 562590..563204 (-) 615 WP_024945430.1 dephospho-CoA kinase -
  L6424_RS02625 (NUITMVA1_05030) pilD 563224..564096 (-) 873 WP_024945429.1 prepilin peptidase Machinery gene
  L6424_RS02630 (NUITMVA1_05040) pilC 564119..565360 (-) 1242 WP_011707570.1 type II secretion system F family protein Machinery gene
  L6424_RS02635 (NUITMVA1_05050) pilB 565476..567182 (-) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  L6424_RS02640 (NUITMVA1_05060) - 567186..567608 (-) 423 WP_024944770.1 pilin -
  L6424_RS02645 (NUITMVA1_05070) nadC 567931..568788 (-) 858 WP_024944771.1 carboxylating nicotinate-nucleotide diphosphorylase -
  L6424_RS02650 (NUITMVA1_05080) - 568794..569264 (-) 471 WP_024944772.1 TIGR02281 family clan AA aspartic protease -
  L6424_RS02655 (NUITMVA1_05090) ampD 569411..569983 (+) 573 WP_024944773.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45422.58 Da        Isoelectric Point: 9.8637

>NTDB_id=90933 L6424_RS02630 WP_011707570.1 564119..565360(-) (pilC) [Aeromonas hydrophila strain NUITM-VA1]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=90933 L6424_RS02630 WP_011707570.1 564119..565360(-) (pilC) [Aeromonas hydrophila strain NUITM-VA1]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCGGGCGTACCTCTGGTCCAGAGCCTGCAAATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGGCAGATTGCCGCCGATGTGGAAACCGGCACCCCCATGTCCGAAGCGCTGCGCCGCCATCCCC
GTCACTTTGACGACCTCTACTGCGATCTGGTGGAGGCTGGCGAGCAGTCCGGCGCGCTGGAGACCATCTACGATCGCATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATCGTCGTTACATCCATCCTGCTGCTGTTCGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCATCTTCACCCAATTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATATTGACCAT
CCCGGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACTACCTTCTCCGCCGGCA
TCCCACTGGTGGATGCCTTGGTCTCTGCGGCAGGCGCCTCTGGCAACTATGTCTATCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0KPV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment